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Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine.
Published in:
EMBO Molecular Medicine, 2010, v. 2, n. 5, p. 146, doi. 10.1002/emmm.201000070
By:
- Dias-Santagata, Dora;
- Akhavanfard, Sara;
- David, Serena S.;
- Vernovsky, Kathy;
- Kuhlmann, Georgiana;
- Boisvert, Susan L.;
- Stubbs, Hannah;
- McDermott, Ultan;
- Settleman, Jeffrey;
- Kwak, Eunice L.;
- Clark, Jeffrey W.;
- Isakoff, Steven J.;
- Sequist, Lecia V.;
- Engelman, Jeffrey A.;
- Lynch, Thomas J.;
- Haber, Daniel A.;
- Louis, David N.;
- Ellisen, Leif W.;
- Borger, Darrell R.;
- Iafrate, A. John
Publication type:
Article
Synergistic Effects of Targeted PI3K Signaling Inhibition and Chemotherapy in Liposarcoma.
Published in:
PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0093996
By:
- Guo, Shang;
- Lopez-Marquez, Hector;
- Fan, Kenneth C.;
- Choy, Edwin;
- Cote, Gregory;
- Harmon, David;
- Nielsen, G. Petur;
- Yang, Cao;
- Zhang, Changqing;
- Mankin, Henry;
- Hornicek, Francis J.;
- Borger, Darrell R.;
- Duan, Zhenfeng
Publication type:
Article
Inhibition of Hedgehog Signaling Antagonizes Serous Ovarian Cancer Growth in a Primary Xenograft Model.
Published in:
PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0028077
By:
- McCann, Christopher K.;
- Growdon, Whitfield B.;
- Kulkarni-Datar, Kashmira;
- Curley, Michael D.;
- Friel, Anne M.;
- Proctor, Jennifer L.;
- Sheikh, Hana;
- Deyneko, Igor;
- Ferguson, Jeanne A.;
- Vathipadiekal, Vinod;
- Birrer, Michael J.;
- Borger, Darrell R.;
- Mohapatra, Gayatry;
- Zukerberg, Lawrence R.;
- Foster, Rosemary;
- MacDougall, John R.;
- Rueda, Bo R.
Publication type:
Article
BRAF V600E Mutations Are Common in Pleomorphic Xanthoastrocytoma: Diagnostic and Therapeutic Implications.
Published in:
PLoS ONE, 2011, v. 6, n. 3, p. 1, doi. 10.1371/journal.pone.0017948
By:
- Dias-Santagata, Dora;
- Quynh Lam;
- Vernovsky, Kathy;
- Vena, Natalie;
- Lennerz, Jochen K.;
- Borger, Darrell R.;
- Batchelor, Tracy T.;
- Ligon, Keith L.;
- Iafrate, A. John;
- Ligon, Azra H.;
- Louis, David N.;
- Santagata, Sandro
Publication type:
Article
PIK3CA activating mutations are associated with more disseminated disease at presentation and earlier recurrence in glioblastoma.
Published in:
Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40478-019-0720-8
By:
- Tanaka, Shota;
- Batchelor, Tracy T.;
- Iafrate, A. John;
- Dias-Santagata, Dora;
- Borger, Darrell R.;
- Ellisen, Leif W.;
- Yang, Daniel;
- Louis, David N.;
- Cahill, Daniel P.;
- Chi, Andrew S.
Publication type:
Article
Primary tumor sidedness is an independent prognostic marker for survival in metastatic colorectal cancer: Results from a large retrospective cohort with mutational analysis.
Published in:
Cancer Medicine, 2018, v. 7, n. 7, p. 2934, doi. 10.1002/cam4.1558
By:
- Kamran, Sophia C.;
- Clark, Jeffrey W.;
- Zheng, Hui;
- Borger, Darrell R.;
- Blaszkowsky, Lawrence S.;
- Allen, Jill N.;
- Kwak, Eunice L.;
- Wo, Jennifer Y.;
- Parikh, Aparna R.;
- Nipp, Ryan D.;
- Murphy, Janet E.;
- Goyal, Lipika;
- Zhu, Andrew X.;
- Iafrate, A. John;
- Corcoran, Ryan B.;
- Ryan, David P.;
- Hong, Theodore S.
Publication type:
Article
Epigenetic regulation of CD133 and tumorigenicity of CD133 positive and negative endometrial cancer cells.
Published in:
Reproductive Biology & Endocrinology, 2010, v. 8, p. 147, doi. 10.1186/1477-7827-8-147
By:
- Friel, Anne M.;
- Ling Zhang;
- Curley, Michael D.;
- Therrien, Vanessa A.;
- Sergent, Petra A.;
- Belden, Sarah E.;
- Borger, Darrell R.;
- Mohapatra, Gayatry;
- Zukerberg, Lawrence R.;
- Foster, Rosemary;
- Rueda, Bo R.
Publication type:
Article
BRAF mutation in 'sarcomas': a possible method to detect de-differentiated melanomas.
Published in:
Histopathology, 2014, v. 64, n. 5, p. 639, doi. 10.1111/his.12305
By:
- Cipriani, Nicole A;
- Letovanec, Igor;
- Hornicek, Francis J;
- Mullen, John T;
- Duan, Zhenfeng;
- Borger, Darrell R;
- Nielsen, Gunnlaugur Petur
Publication type:
Article
RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer.
Published in:
Nature Communications, 2015, v. 6, n. 3, p. 6377, doi. 10.1038/ncomms7377
By:
- Niederst, Matthew J.;
- Sequist, Lecia V.;
- Poirier, John T.;
- Mermel, Craig H.;
- Lockerman, Elizabeth L.;
- Garcia, Angel R.;
- Katayama, Ryohei;
- Costa, Carlotta;
- Ross, Kenneth N.;
- Moran, Teresa;
- Howe, Emily;
- Fulton, Linnea E.;
- Mulvey, Hillary E.;
- Bernardo, Lindsay A.;
- Mohamoud, Farhiya;
- Miyoshi, Norikatsu;
- VanderLaan, Paul A.;
- Costa, Daniel B.;
- Jänne, Pasi A.;
- Borger, Darrell R.
Publication type:
Article
Inactivation of the tumor suppressor WTX in a subset of pediatric tumors.
Published in:
Genes, Chromosomes & Cancer, 2014, v. 53, n. 1, p. 67, doi. 10.1002/gcc.22118
By:
- Akhavanfard, Sara;
- Vargas, Sara O.;
- Han, Moonjoo;
- Nitta, Mai;
- Chang, Clarice B.;
- Le, Long P.;
- Fazlollahi, Ladan;
- Nguyen, Quan;
- Ma, Yunqing;
- Cosper, Arjola;
- Dias‐Santagata, Dora;
- Han, Jae Y.;
- Bergethon, Kristin;
- Borger, Darrell R.;
- Ellisen, Leif W.;
- Pomeroy, Scott L.;
- Haber, Daniel A.;
- Iafrate, A. John;
- Rivera, Miguel N.
Publication type:
Article
A phase 2 and biomarker study of cabozantinib in patients with advanced cholangiocarcinoma.
Published in:
2017
By:
- Goyal, Lipika;
- Zheng, Hui;
- Yurgelun, Matthew B.;
- Abrams, Thomas A.;
- Allen, Jill N.;
- Cleary, James M.;
- Knowles, Michelle;
- Regan, Eileen;
- Reardon, Amanda;
- Khachatryan, Anna;
- Jain, Rakesh K.;
- Nardi, Valentina;
- Borger, Darrell R.;
- Duda, Dan G.;
- Zhu, Andrew X.
Publication type:
journal article
Mutational analysis and clinical correlation of metastatic colorectal cancer.
Published in:
Cancer (0008543X), 2014, v. 120, n. 10, p. 1482, doi. 10.1002/cncr.28599
By:
- Russo, Andrea L.;
- Borger, Darrell R.;
- Szymonifka, Jackie;
- Ryan, David P.;
- Wo, Jennifer Y.;
- Blaszkowsky, Lawrence S.;
- Kwak, Eunice L.;
- Allen, Jill N.;
- Wadlow, Raymond C.;
- Zhu, Andrew X.;
- Murphy, Janet E.;
- Faris, Jason E.;
- Dias‐Santagata, Dora;
- Haigis, Kevin M.;
- Ellisen, Leif W.;
- Iafrate, Anthony J.;
- Hong, Theodore S.
Publication type:
Article
Phase 1/2 study of everolimus in advanced hepatocellular carcinoma.
Published in:
Cancer (0008543X), 2011, v. 117, n. 22, p. 5094, doi. 10.1002/cncr.26165
By:
- Zhu, Andrew X.;
- Abrams, Thomas A.;
- Miksad, Rebecca;
- Blaszkowsky, Lawrence S.;
- Meyerhardt, Jeffrey A.;
- Zheng, Hui;
- Muzikansky, Alona;
- Clark, Jeffrey W.;
- Kwak, Eunice L.;
- Schrag, Deborah;
- Jors, Kathryn R.;
- Fuchs, Charles S.;
- Iafrate, A. John;
- Borger, Darrell R.;
- Ryan, David P.
Publication type:
Article
Revisiting MET: Clinical Characteristics and Treatment Outcomes of Patients with Locally Advanced or Metastatic, MET‐Amplified Esophagogastric Cancers.
Published in:
Oncologist, 2020, v. 25, n. 11, p. e1691, doi. 10.1634/theoncologist.2020-0274
By:
- Chaudhary, Surendra Pal;
- Kwak, Eunice L.;
- Hwang, Katie L.;
- Lennerz, Jochen K.;
- Corcoran, Ryan B.;
- Heist, Rebecca S.;
- Russo, Andrea L.;
- Parikh, Aparna;
- Borger, Darrell R.;
- Blaszkowsky, Lawrence S.;
- Faris, Jason E.;
- Murphy, Janet E.;
- Azzoli, Christopher G.;
- Roeland, Eric J.;
- Goyal, Lipika;
- Allen, Jill;
- Mullen, John T.;
- Ryan, David P.;
- Iafrate, A. John;
- Klempner, Samuel J.
Publication type:
Article
Enrichment of HER2 Amplification in Brain Metastases from Primary Gastrointestinal Malignancies.
Published in:
Oncologist, 2019, v. 24, n. 2, p. 193, doi. 10.1634/theoncologist.2018-0152
By:
- Mitra, Devarati;
- Clark, Jeffrey W.;
- Shih, Helen A.;
- Oh, Kevin S.;
- Brastianos, Priscilla K.;
- Wo, Jennifer Y.;
- Strickland, Matthew R.;
- Curry, William T.;
- Parikh, Aparna R.;
- Corcoran, Ryan B.;
- Ryan, David P.;
- Iafrate, A. John;
- Borger, Darrell R.;
- Lennerz, Jochen K.;
- Hong, Theodore S.
Publication type:
Article
Elevation of Urinary 2-Hydroxyglutarate in IDH-Mutant Glioma.
Published in:
Oncologist, 2016, v. 21, n. 2, p. 214, doi. 10.1634/theoncologist.2015-0342
By:
- Fathi, Amir T.;
- Nahed, Brian V.;
- Wander, Seth A.;
- Iafrate, A. John;
- Borger, Darrell R.;
- Hu, Ranliang;
- Thabet, Ashraf;
- Cahill, Daniel P.;
- Perry, Ashley M.;
- Joseph, Christelle P.;
- Muzikansky, Alona;
- Chi, Andrew S.
Publication type:
Article
Prognosis and Clinicopathologic Features of Patients With Advanced Stage Isocitrate Dehydrogenase (IDH) Mutant and IDH Wild-Type Intrahepatic Cholangiocarcinoma.
Published in:
Oncologist, 2015, v. 20, n. 9, p. 1019, doi. 10.1634/theoncologist.2015-0210
By:
- Goyal, Lipika;
- Govindan, Aparna;
- Sheth, Rahul A.;
- Nardi, Valentina;
- Blaszkowsky, Lawrence S.;
- Faris, Jason E.;
- Clark, Jeffrey W.;
- Ryan, David P.;
- Kwak, Eunice L.;
- Allen, Jill N.;
- Murphy, Janet E.;
- Saha, Supriya K.;
- Hong, Theodore S.;
- Wo, Jennifer Y.;
- Ferrone, Cristina R.;
- Tanabe, Kenneth K.;
- Chong, Dawn Q.;
- Deshpande, Vikram;
- Borger, Darrell R.;
- Iafrate, A. John
Publication type:
Article
Isocitrate Dehydrogenase 1 (IDH1) Mutation in Breast Adenocarcinoma Is Associated With Elevated Levels of Serum and Urine 2-Hydroxyglutarate.
Published in:
Oncologist, 2014, v. 19, n. 6, p. 602, doi. 10.1634/theoncologist.2013-0417
By:
- Fathi, Amir T.;
- Sadrzadeh, Hossein;
- Comander, Amy H.;
- Higgins, Michaela J.;
- Bardia, Aditya;
- Perry, Ashley;
- Burke, Meghan;
- Silver, Regina;
- Matulis, Christina R.;
- Straley, Kimberly S.;
- Yen, Katharine E.;
- Agresta, Sam;
- Kim, Hyeryun;
- Schenkein, David P.;
- Borger, Darrell R.
Publication type:
Article
Frequent Mutation of Isocitrate Dehydrogenase (IDH)1 and IDH2 in Cholangiocarcinoma Identified Through Broad-Based Tumor Genotyping.
Published in:
Oncologist, 2012, v. 17, n. 1, p. 72, doi. 10.1634/theoncologist.2011-0386
By:
- BORGER, DARRELL R.;
- TANABE, KENNETH K.;
- FAN, KENNETH C.;
- LOPEZ, HECTOR U.;
- FANTIN, VALERIA R.;
- STRALEY, KIMBERLY S.;
- SCHENKEIN, DAVID P.;
- HEZEL, ARAM F.;
- ANCUKIEWICZ, MAREK;
- LIEBMAN, HANNAH M.;
- KWAK, EUNICE L.;
- CLARK, JEFFREY W.;
- RYAN, DAVID P.;
- DESHPANDE, VIKRAM;
- DIAS-SANTAGATA, DORA;
- ELLISEN, LEIF W.;
- ZHU, ANDREW X.;
- IAFRATE, A. JOHN
Publication type:
Article
Targeted sequencing of SMO and AKT1 in anterior skull base meningiomas.
Published in:
Journal of Neurosurgery, 2017, v. 127, n. 2, p. 438, doi. 10.3171/2016.8.JNS161076
By:
- Strickland, Matthew R.;
- Gill, Corey M.;
- Nayyar, Naema;
- D'Andrea, Megan R.;
- Thiede, Christian;
- Juratli, Tareq A.;
- Schackert, Gabriele;
- Borger, Darrell R.;
- Santagata, Sandro;
- Frosch, Matthew P.;
- Cahill, Daniel P.;
- Brastianos, Priscilla K.;
- Barker II, Fred G.
Publication type:
Article
Phase II Study of Proton-Based Stereotactic Body Radiation Therapy for Liver Metastases: Importance of Tumor Genotype.
Published in:
2017
By:
- Hong, Theodore S;
- Wo, Jennifer Y;
- Borger, Darrell R;
- Yeap, Beow Y;
- McDonnell, Erin I;
- Willers, Henning;
- Blaszkowsky, Lawrence S;
- Kwak, Eunice L;
- Allen, Jill N;
- Clark, Jeffrey W;
- Tanguturi, Shyam;
- Goyal, Lipika;
- Murphy, Janet E;
- Wolfgang, John A;
- Drapek, Lorraine C;
- Arellano, Ronald S;
- Mamon, Harvey J;
- Mullen, John T;
- Tanabe, Kenneth K;
- Ferrone, Cristina R
Publication type:
journal article

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