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- Title
Radiological-pathological correlation in lipoblastoma and lipoblastomatosis.
- Authors
Moholkar, Shruti; Sebire, Neil J.; Roebuck, Derek J.
- Abstract
<bold>Background: </bold>Lipoblastoma and lipoblastomatosis are uncommon benign mesenchymal lesions that predominantly occur in infancy and early childhood.<bold>Objective: </bold>To evaluate the imaging and histological features of lipoblastoma and lipoblastomatosis.<bold>Materials and Methods: </bold>Retrospective review of the radiological and pathological findings in children with lipoblastoma and lipoblastomatosis treated at a single centre between 1997 and 2004.<bold>Results: </bold>Eight children (median age 18 months) had undergone imaging and surgery at our institution. An infiltrative growth pattern was identified at imaging in two children with lipoblastomatosis, and a well-defined mass in six children with lipoblastoma. In all patients, imaging showed a lesion composed mostly, but not entirely, of fat. There were no recurrences at follow-up of between 1 and 91 months.<bold>Conclusion: </bold>In infancy and early childhood, the identification of a tumour composed mostly of fat should suggest the diagnosis of lipoblastoma or lipoblastomatosis.
- Subjects
LIPOSARCOMA; ADIPOSE tissue cancer; PRECANCEROUS conditions; MEDICAL imaging systems; PEDIATRIC radiology; MEDICAL radiology; DIAGNOSTIC imaging
- Publication
Pediatric Radiology, 2006, Vol 36, Issue 8, p851
- ISSN
0301-0449
- Publication type
journal article
- DOI
10.1007/s00247-006-0175-5