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Defining and modeling known adverse outcome pathways: Domoic acid and neuronal signaling as a case study.
- Published in:
- Environmental Toxicology & Chemistry, 2011, v. 30, n. 1, p. 9, doi. 10.1002/etc.373
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- Publication type:
- Article
Developmental triclosan exposure decreases maternal and neonatal thyroxine in rats.
- Published in:
- Environmental Toxicology & Chemistry, 2010, v. 29, n. 12, p. 2840, doi. 10.1002/etc.339
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- Publication type:
- Article
Splice variant specific increase in Ca<sup>2+</sup>/calmodulin-dependent protein kinase 1-gamma mRNA expression in response to acute pyrethroid exposure.
- Published in:
- Journal of Biochemical & Molecular Toxicology, 2010, v. 24, n. 3, p. 174, doi. 10.1002/jbt.20324
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- Publication type:
- Article
External Scientific Report on the Interpretation of Data from the Developmental Neurotoxicity In Vitro Testing Assays for Use in Integrated Approaches for Testing and Assessment.
- Published in:
- EFSA Supporting Publications, 2021, v. 18, n. 10, p. 1, doi. 10.2903/sp.efsa.2021.EN-6924
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- Publication type:
- Article
Limited Chemical Structural Diversity Found to Modulate Thyroid Hormone Receptor in the Tox21 Chemical Library.
- Published in:
- Environmental Health Perspectives, 2019, v. 127, n. 9, p. 1, doi. 10.1289/EHP5314
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- Publication type:
- Article
Evaluating Chemicals for Thyroid Disruption: Opportunities and Challenges with in Vitro Testing and Adverse Outcome Pathway Approaches.
- Published in:
- Environmental Health Perspectives, 2019, v. 127, n. 9, p. 1, doi. 10.1289/EHP5297
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- Publication type:
- Article
Comment on "On the Utility of ToxCast™ and ToxPi as Methods for Identifying New Obesogens".
- Published in:
- 2017
- By:
- Publication type:
- Letter to the Editor
The Next Generation of Risk Assessment Multi-Year Study--Highlights of Findings, Applications to Risk Assessment, and Future Directions.
- Published in:
- Environmental Health Perspectives, 2016, v. 124, n. 11, p. 1671, doi. 10.1289/EHP233
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- Publication type:
- Article
Using ToxCast™ Data to Reconstruct Dynamic Cell State Trajectories and Estimate Toxicological Points of Departure.
- Published in:
- Environmental Health Perspectives, 2016, v. 124, n. 7, p. 910, doi. 10.1289/ehp.1409029
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- Publication type:
- Article
Current Perspectives on the Use of Alternative Species in Human Health and Ecological Hazard Assessments.
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- Environmental Health Perspectives, 2013, v. 121, n. 9, p. 1002, doi. 10.1289/ehp.1306638
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- Publication type:
- Article
Using in Vitro High Throughput Screening Assays to Identify Potential Endocrine-Disrupting Chemicals.
- Published in:
- 2013
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- Publication type:
- Journal Article
Supplemental Material. Using in Vitro High-Throughput Screening Assays to Identify Potential Endocrine Disrupting Chemicals.
- Published in:
- Environmental Health Perspectives, 2013, v. 121, n. 1, p. 1, doi. 10.1289/ehp.1205065
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- Publication type:
- Article
Additivity of Pyrethroid Actions on Sodium Influx in Cerebrocortical Neurons in Primary Culture.
- Published in:
- Environmental Health Perspectives, 2011, v. 119, n. 9, p. 1239, doi. 10.1289/ehp.1003394
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- Publication type:
- Article
Evidence for Dose-Additive Effects of Pyrethroids on Motor Activity in Rats.
- Published in:
- Environmental Health Perspectives, 2009, v. 117, n. 10, p. 1563, doi. 10.1289/ehp.0900667
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- Publication type:
- Article
Thyroid-Disrupting Chemicals: Interpreting Upstream Biomarkers of Adverse Outcomes.
- Published in:
- Environmental Health Perspectives, 2009, v. 117, n. 7, p. 1033, doi. 10.1289/ehp.0800247
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- Publication type:
- Article
A Retrospective Performance Assessment of the Developmental Neurotoxicity Study in Support of OECD Test Guideline 426.
- Published in:
- Environmental Health Perspectives, 2009, v. 117, n. 1, p. 17, doi. 10.1289/ehp.11447
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- Publication type:
- Article
Thyroid-Hormone-Disrupting Chemicals: Evidence for Dose-Dependent Additivity or Synergism.
- Published in:
- Environmental Health Perspectives, 2005, v. 113, n. 11, p. 1549, doi. 10.1289/ehp.8195
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- Publication type:
- Article
Developmental Neurotoxicity of Pyrethroid Insecticides: Critical Review and Future Research Needs.
- Published in:
- Environmental Health Perspectives, 2005, v. 113, n. 2, p. 123, doi. 10.1289/ehp.7254
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- Publication type:
- Article
Developmental neurotoxicity testing: A path forward.
- Published in:
- Congenital Anomalies, 2012, v. 52, n. 3, p. 140, doi. 10.1111/j.1741-4520.2012.00377.x
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- Publication type:
- Article
Developmental neurotoxicity guideline study: Issues with methodology, evaluation and regulation* Developmental neurotoxicity guideline study: Issues with methodology, evaluation and regulation.
- Published in:
- Congenital Anomalies, 2012, v. 52, n. 3, p. 122, doi. 10.1111/j.1741-4520.2012.00374.x
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- Publication type:
- Article
The Effects of Triclosan on Puberty and Thyroid Hormones in Male Wistar Rats.
- Published in:
- Toxicological Sciences, 2009, v. 107, n. 1, p. 56, doi. 10.1093/toxsci/kfn225
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- Publication type:
- Article
Low-Dose Effects of Ammonium Perchlorate on the Hypothalamic-Pituitary-Thyroid Axis of Adult Male Rats Pretreated with PCB126.
- Published in:
- Toxicological Sciences, 2007, v. 97, n. 2, p. 308, doi. 10.1093/toxsci/kfm063
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- Publication type:
- Article
Inhalational Exposure to Carbonyl Sulfide Produces Altered Brainstem Auditory and Somatosensory-Evoked Potentials in Fischer 344N Rats.
- Published in:
- Toxicological Sciences, 2007, v. 95, n. 1, p. 118, doi. 10.1093/toxsci/kfl146
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- Publication type:
- Article
Effect of PCB 126 on Hepatic Metabolism of Thyroxine and Perturbations in the Hypothalamic-Pituitary-Thyroid Axis in the Rat.
- Published in:
- Toxicological Sciences, 2006, v. 90, n. 1, p. 87, doi. 10.1093/toxsci/kfj069
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- Publication type:
- Article
Accumulation of PBDE-47 in Primary Cultures of Rat Neocortical Cells.
- Published in:
- 2005
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- Publication type:
- Erratum
Accumulation of PBDE-47 in Primary Cultures of Rat Neocortical Cells.
- Published in:
- Toxicological Sciences, 2004, v. 82, n. 1, p. 164, doi. 10.1093/toxsci/kfh239
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- Publication type:
- Article
Assessment of DE-71, a Commercial Polybrominated Diphenyl Ether (PBDE) Mixture, in the EDSP Male and Female Pubertal ProtocolsThe information in this document has been funded wholly by the U.S. Environmental Protection Agency. It has been subjected to review by the National Health and Environmental Effects Research Laboratory and approved for publication. Approval does not signify that the contents necessarily reflect the views of the Agency, nor does mention of trade names or commercial products constitute endorsement or recommendation for use.
- Published in:
- Toxicological Sciences, 2004, v. 78, n. 1, p. 144, doi. 10.1093/toxsci/kfh029
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- Publication type:
- Article
Comparative Responsiveness of Hypothyroxinemia and Hepatic Enzyme Induction in Long-Evans Rats Versus C57BL/6J Mice Exposed to TCDD-like and Phenobarbital-like Polychlorinated Biphenyl Congeners.
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- Toxicological Sciences, 2002, v. 68, n. 2, p. 372, doi. 10.1093/toxsci/68.2.372
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- Publication type:
- Article
Perinatal Exposure to Aroclor 1254 Impairs Distortion Product Otoacoustic Emissions (DPOAEs) in Rats.
- Published in:
- Toxicological Sciences, 2002, v. 68, n. 2, p. 458, doi. 10.1093/toxsci/68.2.458
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- Publication type:
- Article
Developmental Exposure to Brominated Diphenyl Ethers Results in Thyroid Hormone Disruption.
- Published in:
- Toxicological Sciences, 2002, v. 66, n. 1, p. 105, doi. 10.1093/toxsci/66.1.105
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- Publication type:
- Article
Effects of Short-Term in Vivo Exposure to Polybrominated Diphenyl Ethers on Thyroid Hormones and Hepatic Enzyme Activities in Weanling Rats.
- Published in:
- Toxicological Sciences, 2001, v. 61, n. 1, p. 76, doi. 10.1093/toxsci/61.1.76
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- Publication type:
- Article
Gestational-Lactational Exposure to Aroclor 1254 Impairs Radial-Arm Maze Performance in Male Rats.
- Published in:
- Toxicological Sciences, 2000, v. 57, n. 1, p. 121, doi. 10.1093/toxsci/57.1.121
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- Publication type:
- Article
Thyroxine Replacement Attenuates Hypothyroxinemia, Hearing Loss, and Motor Deficits Following Developmental Exposure to Aroclor 1254 in Rats 1.
- Published in:
- Toxicological Sciences, 1998, v. 45, n. 1, p. 94, doi. 10.1093/toxsci/45.1.94
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- Publication type:
- Article
Trichloroethylene Ototoxicity: Evidence for a Cochlear Origin1.
- Published in:
- Toxicological Sciences, 1998, v. 42, n. 1, p. 28, doi. 10.1093/toxsci/42.1.28
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- Publication type:
- Article
Corrigendum to Recommendation on Test Readiness Criteria for New Approach Methods in Toxicology: Exemplified for Developmental Neurotoxicity.
- Published in:
- Altex, 2019, v. 36, n. 3, p. 506, doi. 10.14573/altex.1904112
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- Publication type:
- Article
Recommendation on Test Readiness Criteria for New Approach Methods in Toxicology: Exemplified for Developmental Neurotoxicity.
- Published in:
- Altex, 2018, v. 35, n. 3, p. 306, doi. 10.14573/altex.1712081
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- Publication type:
- Article
The US Federal Tox21 Program: A Strategic and Operational Plan for Continued Leadership.
- Published in:
- Altex, 2018, v. 35, n. 2, p. 163, doi. 10.14573/altex.1803011
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- Publication type:
- Article
OECD/EFSA Workshop on Developmental Neurotoxicity (DNT): The Use of Non-Animal Test Methods for Regulatory Purposes.
- Published in:
- Altex, 2017, v. 34, n. 2, p. 311, doi. 10.14573/altex.1701171
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- Publication type:
- Article
The Human Toxome Project.
- Published in:
- Altex, 2015, v. 32, n. 2, p. 112, doi. 10.14573/altex.1502091
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- Publication type:
- Article
Pathways of Toxicity.
- Published in:
- Altex, 2014, p. 53, doi. 10.14573/altex.1309261
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- Publication type:
- Article
Advancing the Science of Developmental Neurotoxicity (DNT): Testing for Better Safety Evaluation.
- Published in:
- Altex, 2012, v. 29, n. 2, p. 202, doi. 10.14573/altex.2012.2.202
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- Publication type:
- Article
A developmental neurotoxicity adverse outcome pathway (DNT‐AOP) with voltage gate sodium channel (VGSC) inhibition as a molecular initiating event (MiE).
- Published in:
- EFSA Journal, 2024, v. 22, n. 8, p. 1, doi. 10.2903/j.efsa.2024.8954
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- Publication type:
- Article
International Regulatory and Scientific Effort for Improved Developmental Neurotoxicity Testing.
- Published in:
- Toxicological Sciences, 2019, v. 167, n. 1, p. 45, doi. 10.1093/toxsci/kfy211
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- Publication type:
- Article
FutureTox III: Bridges for Translation.
- Published in:
- Toxicological Sciences, 2017, v. 155, n. 1, p. 22, doi. 10.1093/toxsci/kfw194
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- Publication type:
- Article
Tiered High-Throughput Screening Approach to Identify Thyroperoxidase Inhibitors Within the ToxCast Phase I and II Chemical Libraries.
- Published in:
- Toxicological Sciences, 2016, v. 151, n. 1, p. 160, doi. 10.1093/toxsci/kfw034
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- Publication type:
- Article
Integrated Model of Chemical Perturbations of a Biological Pathway Using 18 In Vitro High-Throughput Screening Assays for the Estrogen Receptor.
- Published in:
- Toxicological Sciences, 2015, v. 148, n. 1, p. 137, doi. 10.1093/toxsci/kfv168
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- Publication type:
- Article
An Animal Model of Marginal Iodine Deficiency During Development: The Thyroid Axis and Neurodevelopmental Outcome*.
- Published in:
- Toxicological Sciences, 2013, v. 132, n. 1, p. 177, doi. 10.1093/toxsci/kfs335
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- Publication type:
- Article
In Vitro Perturbations of Targets in Cancer Hallmark Processes Predict Rodent Chemical Carcinogenesis.
- Published in:
- Toxicological Sciences, 2013, v. 131, n. 1, p. 40, doi. 10.1093/toxsci/kfs285
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- Publication type:
- Article
Environmentally Relevant Mixtures in Cumulative Assessments: An Acute Study of Toxicokinetics and Effects on Motor Activity in Rats Exposed to a Mixture of Pyrethroids.
- Published in:
- Toxicological Sciences, 2012, v. 130, n. 2, p. 309, doi. 10.1093/toxsci/kfs245
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- Publication type:
- Article
Rebuttal of “Flawed Experimental Design Reveals the Need for Guidelines Requiring Appropriate Positive Controls in Endocrine Disruption Research” by vom Saal.
- Published in:
- 2010
- By:
- Publication type:
- Letter