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- Title
Oral dissolving film: present and future aspects.
- Authors
Prabhjot, Kaur; Rajeev, Garg
- Abstract
Over the past few decades, tendency toward innovative drug delivery systems has almightily increased attempts to ensure efficacy, safety and patient acceptability. As discovery and development of new chemical agents is a complex, expensive and time consuming process, so recent trends are shifting toward designing and developing innovative drug delivery systems for existing drugs. Orally fast dissolving film is the kind of drug delivery system which when placed in the oral cavity, disintegrate or dissolve within a few seconds without the intake of water. Oral fast dissolving film is relatively new dosage form in which thin film is prepared using hydrophilic polymers, which rapidly disintegrate or dissolves on tongue or in the buccal cavity It is an alternative platform for molecules that undergoes high first pass metabolism. The method of preparation for oral dissolving film. Solvent casting, Semisolid casting, Hot melt extrusion, Solid dispersion extrusion, Rolling The current evaluation gives an account of different formulations methods of preparation and quality control of the fast dissolving oral thin film.
- Subjects
BIOFILMS; DRUG delivery systems; DRUG efficacy; DRUG dosage; TENSILE strength
- Publication
Journal of Drug Delivery & Therapeutics, 2018, Vol 8, Issue 6, p373
- ISSN
2250-1177
- Publication type
Article
- DOI
10.22270/jddt.v8i6.2050