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- Title
Primary cutaneous lymphomas: diagnosis and treatment.
- Authors
Sokołowska-Wojdyło, Małgorzata; Olek-Hrab, Karolina; Ruckemann-Dziurdzińska, Katarzyna
- Abstract
Primary cutaneous lymphomas (CLs) are a heterogeneous group of lymphoproliferative neoplasms, with lymphatic proliferation limited to the skin with no involvement of lymph nodes, bone marrow or viscera at the diagnosis. Cutaneous lymphomas originate from mature T-lymphocytes (65% of all cases), mature B-lymphocytes (25%) or NK cells. Histopathological evaluation including immunophenotyping of the skin biopsy specimen is the basis of the diagnosis, which must be complemented with a precise staging of the disease and identification of prognostic factors, to allow for the choice of the best treatment method as well as for the evaluation of the treatment results.
- Subjects
LYMPHOMA diagnosis; LYMPHOMAS; CELL proliferation; LYMPH nodes; BONE marrow; HISTOPATHOLOGY; IMMUNOPHENOTYPING; PROGNOSIS
- Publication
Advances in Dermatology & Allergology / Postępy Dermatologii i Alergologii, 2015, Vol 32, Issue 5, p368
- ISSN
1642-395X
- Publication type
Article
- DOI
10.5114/pdia.2015.54749