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- Title
Decreased IRF8 expression found in aging hematopoietic progenitor/stem cells.
- Authors
Stirewalt, D. L.; Choi, Y. E.; Sharpless, N. E.; Pogosova-Agadjanyan, E. L.; Cronk, M. R.; Yukawa, M.; Larson, E. B.; Wood, B. L.; Appelbaum, F. R.; Radich, J. P.; Heimfeld, S.
- Abstract
A letter to the editor is presented about the decrease of interferon regulatory factor 8 (IRF8) expression that is commonly found in aging hematopoietic cells, which may contribute to myeloid skewing and the development of hematopoietic diseases in older adults.
- Subjects
LETTERS to the editor; INTERFERONS; PROTEIN analysis; AGE distribution; AGING; ANIMALS; ANTIGENS; HEMATOPOIETIC stem cells; MICE; PROTEINS
- Publication
Leukemia (08876924), 2009, Vol 23, Issue 2, p391
- ISSN
0887-6924
- Publication type
letter
- DOI
10.1038/leu.2008.176