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Intranasal NAP (davunetide) decreases tau hyperphosphorylation and moderately improves behavioral deficits in mice overexpressing α-synuclein.
Published in:
Pharmacology Research & Perspectives, 2014, v. 2, n. 5, p. n/a, doi. 10.1002/prp2.65
By:
- Magen, Iddo;
- Ostritsky, Regina;
- Richter, Franziska;
- Zhu, Chunni;
- Fleming, Sheila M.;
- Lemesre, Vincent;
- Stewart, Alistair J.;
- Morimoto, Bruce H.;
- Gozes, Illana;
- Chesselet, Marie ‐ Françoise
Publication type:
Article
A de novo compound targeting α-synuclein improves deficits in models of Parkinson's disease.
Published in:
2016
By:
- Wrasidlo, Wolfgang;
- Tsigelny, Igor F.;
- Price, Diana L.;
- Dutta, Garima;
- Rockenstein, Edward;
- Schwarz, Thomas C.;
- Ledolter, Karin;
- Bonhaus, Douglas;
- Paulino, Amy;
- Eleuteri, Simona;
- Skjevik, Åge A.;
- Kouznetsova, Valentina L.;
- Spencer, Brian;
- Desplats, Paula;
- Gonzalez-Ruelas, Tania;
- Trejo-Morales, Margarita;
- Overk, Cassia R.;
- Winter, Stefan;
- Chunni Zhu;
- Chesselet, Marie-Francoise
Publication type:
journal article
P4‐709: PROTEOLIPIDOME ANALYSIS OF HIPPOCAMPAL TISSUE FROM A MURINE ALZHEIMER'S DISEASE MODEL TO FACILITATE THERAPEUTIC TARGET IDENTIFICATION.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1604, doi. 10.1016/j.jalz.2019.09.073
By:
- Cohn, Whitaker;
- Campagna, Jesus J.;
- Spilman, Patricia;
- Elias, Chris Jean;
- Zhu, Chunni;
- Bilousova, Tina;
- Faull, Kym F.;
- Whitelegge, Julian;
- John, Varghese
Publication type:
Article
P4‐057: PURIFICATION AND CHARACTERIZATION OF SUBPOPULATIONS OF EXTRACELLULAR VESICLES FROM AD AND PD BRAIN AND THEIR SUPPRESSION BY NSMASE2 INHIBITORS.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1294, doi. 10.1016/j.jalz.2019.06.3717
By:
- Bilousova, Tina;
- Elias, Chris Jean;
- Melnik, Mikhail;
- Miyoshi, Emily;
- Campagna, Jesus J.;
- Simmons, Bryan;
- Hatami, Asa;
- Zhu, Chunni;
- Jun, Michael;
- Cohn, Whitaker;
- Jagodzinska, Barbara;
- Vadivel, Kanagasabai;
- Spilman, Patricia;
- Garg, Neil;
- Gylys, Karen H.;
- John, Varghese
Publication type:
Article
P2‐176: IDENTIFICATION OF AN EXPERIMENTAL DRUG THAT ENHANCES BRAIN SIRTUIN 1 LEVELS AND IMPROVES COGNITION AS A POTENTIAL NEW THERAPEUTIC FOR AD.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P644, doi. 10.1016/j.jalz.2019.06.2583
By:
- Campagna, Jesus J.;
- Spilman, Patricia;
- Elias, Chris Jean;
- Zhu, Chunni;
- Bilousova, Tina;
- Jun, Michael;
- Bai, Dongsheng;
- Pham, Johnny;
- Kim, Young Sug;
- Bredesen, Dale E.;
- Jung, Michael;
- John, Varghese
Publication type:
Article
O5‐06‐06: NORMALIZATION OF HIPPOCAMPAL SIRTUIN 1 LEVELS IN A MURINE APOLIPOPROTEIN E4‐5XFAD MODEL OF AD RESTORES COGNITIVE FUNCTION.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1659, doi. 10.1016/j.jalz.2018.06.3030
By:
- Spilman, Patricia;
- Campagna, Jesus;
- Jagodzinska, Barbara;
- Zhu, Chunni;
- Bai, Dongsheng;
- Hatami, Asa;
- Bilousova, Tina;
- Jun, Michael;
- Alam, Mohammad Parvez;
- Elias, Chris Jean;
- Soler, Josh;
- Bredesen, Dale E.;
- John, Varghese
Publication type:
Article
Integrated Multiomics Analysis of Salivary Exosomes to Identify Biomarkers Associated with Changes in Mood States and Fatigue.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 9, p. 5257, doi. 10.3390/ijms23095257
By:
- Cohn, Whitaker;
- Zhu, Chunni;
- Campagna, Jesus;
- Bilousova, Tina;
- Spilman, Patricia;
- Teter, Bruce;
- Li, Feng;
- Guo, Rong;
- Elashoff, David;
- Cole, Greg M.;
- Avidan, Alon;
- Faull, Kym Francis;
- Whitelegge, Julian;
- Wong, David T. W.;
- John, Varghese
Publication type:
Article
Epidural Spinal Cord Stimulation Improves Motor Function in Rats With Chemically Induced Parkinsonism.
Published in:
Neurorehabilitation & Neural Repair, 2019, v. 33, n. 12, p. 1029, doi. 10.1177/1545968319876891
By:
- Zhong, Hui;
- Zhu, Chunni;
- Minegishi, Yoshihiko;
- Richter, Franziska;
- Zdunowski, Sharon;
- Roy, Roland R.;
- Vissel, Bryce;
- Gad, Parag;
- Gerasimenko, Yury;
- Chesselet, Marie-Francoise;
- Edgerton, V. Reggie
Publication type:
Article
Multi-Omics Analysis of Microglial Extracellular Vesicles From Human Alzheimer's Disease Brain Tissue Reveals Disease-Associated Signatures.
Published in:
Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.766082
By:
- Cohn, Whitaker;
- Melnik, Mikhail;
- Huang, Calvin;
- Teter, Bruce;
- Chandra, Sujyoti;
- Zhu, Chunni;
- McIntire, Laura Beth;
- John, Varghese;
- Gylys, Karen H.;
- Bilousova, Tina
Publication type:
Article
Phenotype onset in Huntington's disease knock‐in mice is correlated with the incomplete splicing of the mutant huntingtin gene.
Published in:
Journal of Neuroscience Research, 2019, v. 97, n. 12, p. 1590, doi. 10.1002/jnr.24493
By:
- Franich, Nicholas R.;
- Hickey, Miriam A.;
- Zhu, Chunni;
- Osborne, Georgina F.;
- Ali, Nadira;
- Chu, Tiffany;
- Bove, Nicholas H.;
- Lemesre, Vincent;
- Lerner, Renata P.;
- Zeitlin, Scott O.;
- Howland, David;
- Neueder, Andreas;
- Landles, Christian;
- Bates, Gillian P.;
- Chesselet, Marie‐Francoise
Publication type:
Article
Imaging Brain Amyloid of Alzheimer Disease In Vivo in Transgenic Mice With an Aβ Peptide Radiopharmaceutical.
Published in:
Journal of Cerebral Blood Flow & Metabolism, 2002, v. 22, n. 2, p. 223, doi. 10.1097/00004647-200202000-00010
By:
- Lee, Hwa Jeong;
- Zhang, Yun;
- Zhu, Chunni;
- Duff, Karen;
- Pardridge, William M
Publication type:
Article
Use Of Weighted Gene Coexpression Network Analysis To Identify Connectivity Between Gut And Brain Gene Expression.
Published in:
FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R4859
By:
- Khan, Tasnin;
- Hatami, Asa;
- Zhu, Chunni;
- Kawaguchi, Riki;
- Joshi, Swapna;
- Chen, Han;
- Hoffman, Jill;
- Law, Ivy K. M.;
- Rankin, Carl R.;
- John, Varghese;
- Geschwind, Daniel;
- Pothoulakis, Charalabos;
- Videlock, Elizabeth J.
Publication type:
Article
Deuterium‐reinforced linoleic acid lowers lipid peroxidation and mitigates cognitive impairment in the Q140 knock in mouse model of Huntington's disease.
Published in:
FEBS Journal, 2018, v. 285, n. 16, p. 3002, doi. 10.1111/febs.14590
By:
- Hatami, Asa;
- Zhu, Chunni;
- Relaño‐Gines, Aroa;
- Elias, Chris;
- Galstyan, Arpine;
- Jun, Michael;
- Milne, Ginger;
- Cantor, Charles R.;
- Chesselet, Marie‐Francoise;
- Shchepinov, Mikhail S.
Publication type:
Article
Organ-specific expression of the lacZ gene controlled by the opsin promoter after intravenous gene administration in adult mice.
Published in:
Journal of Gene Medicine, 2004, v. 6, n. 8, p. 906, doi. 10.1002/jgm.575
By:
- Zhu, Chunni;
- Zhang, Yun;
- Zhang, Yu-feng;
- Yi Li, Jian;
- Boado, Ruben J.;
- Pardridge, William M.
Publication type:
Article
Antisense Gene Therapy of Brain Cancer with an Artificial Virus Gene Delivery System
Published in:
Molecular Therapy, 2002, v. 6, n. 1, p. 67, doi. 10.1006/mthe.2002.0633
By:
- Zhang, Yun;
- Zhu, Chunni;
- Pardridge, William M.
Publication type:
Article
Cognitive deficits in a mouse model of pre-manifest Parkinson's disease.
Published in:
European Journal of Neuroscience, 2012, v. 35, n. 6, p. 870, doi. 10.1111/j.1460-9568.2012.08012.x
By:
- Magen, Iddo;
- Fleming, Sheila M.;
- Zhu, Chunni;
- Garcia, Eddie C.;
- Cardiff, Katherine M.;
- Dinh, Diana;
- De La Rosa, Krystal;
- Sanchez, Maria;
- Torres, Eileen Ruth;
- Masliah, Eliezer;
- David Jentsch, J.;
- Chesselet, Marie‐Françoise
Publication type:
Article
A small molecule ApoE4-targeted therapeutic candidate that normalizes sirtuin 1 levels and improves cognition in an Alzheimer's disease mouse model.
Published in:
Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-35687-8
By:
- Campagna, Jesus;
- Spilman, Patricia;
- Jagodzinska, Barbara;
- Bai, Dongsheng;
- Hatami, Asa;
- Zhu, Chunni;
- Bilousova, Tina;
- Jun, Michael;
- Elias, Chris Jean;
- Pham, Johnny;
- Cole, Gregory;
- LaDu, Mary Jo;
- Jung, Michael E.;
- Bredesen, Dale E.;
- John, Varghese
Publication type:
Article
Correction to: Pharmacological inhibition of nSMase2 reduces brain exosome release and α-synuclein pathology in a Parkinson's disease model.
Published in:
2021
By:
- Zhu, Chunni;
- Bilousova, Tina;
- Focht, Samantha;
- Jun, Michael;
- Elias, Chris Jean;
- Melnik, Mikhail;
- Chandra, Sujyoti;
- Campagna, Jesus;
- Cohn, Whitaker;
- Hatami, Asa;
- Spilman, Patricia;
- Gylys, Karen Hoppens;
- John, Varghese
Publication type:
Correction Notice
Pharmacological inhibition of nSMase2 reduces brain exosome release and α-synuclein pathology in a Parkinson's disease model.
Published in:
Molecular Brain, 2021, v. 14, n. 1, p. 1, doi. 10.1186/s13041-021-00776-9
By:
- Zhu, Chunni;
- Bilousova, Tina;
- Focht, Samantha;
- Jun, Michael;
- Elias, Chris Jean;
- Melnik, Mikhail;
- Chandra, Sujyoti;
- Campagna, Jesus;
- Cohn, Whitaker;
- Hatami, Asa;
- Spilman, Patricia;
- Gylys, Karen Hoppens;
- John, Varghese
Publication type:
Article
Pharmacological inhibition of nSMase2 reduces brain exosome release and α-synuclein pathology in a Parkinson's disease model.
Published in:
Molecular Brain, 2021, v. 14, n. 1, p. 1, doi. 10.1186/s13041-021-00776-9
By:
- Zhu, Chunni;
- Bilousova, Tina;
- Focht, Samantha;
- Jun, Michael;
- Elias, Chris Jean;
- Melnik, Mikhail;
- Chandra, Sujyoti;
- Campagna, Jesus;
- Cohn, Whitaker;
- Hatami, Asa;
- Spilman, Patricia;
- Gylys, Karen Hoppens;
- John, Varghese
Publication type:
Article

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