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Complaint management of a quality defect in a nanoparticulate Imiquimod formulation in an investigator initiated academic phase I/II clinical trial Part 2.
Published in:
Pharmazeutische Industrie (Pharmind), 2023, v. 85, n. 3, p. 294
By:
- Pielenhofer, Jonas;
- Meiser, Sophie Luise;
- Gogoll, Karsten;
- Ciciliani, Anna-Maria;
- Klak, Michael;
- Lang, Berenice;
- Staubach-Renz, Petra;
- Grabbe, Stephan;
- Schild, Hansjörg;
- Radsak, Markus P.;
- Spahn-Langguth, Hilde;
- Langguth, Peter
Publication type:
Article
Complaint management of a quality defect in a nanoparticulate Imiquimod formulation in an investigator initiated academic phase I/II clinical trial.
Published in:
Pharmazeutische Industrie (Pharmind), 2023, v. 85, n. 2, p. 182
By:
- Pielenhofer, Jonas;
- Meiser, Sophie Luise;
- Gogoll, Karsten;
- Ciciliani, Anna-Maria;
- Klak, Michael;
- Lang, Berenice;
- Staubach-Renz, Petra;
- Grabbe, Stephan;
- Schild, Hansjörg;
- Radsak, Markus P.;
- Spahn-Langguth, Hilde;
- Langguth, Peter
Publication type:
Article
Immunomodulation of neutrophil granulocyte functions by bacterial polyphosphates.
Published in:
European Journal of Immunology, 2023, v. 53, n. 5, p. 1, doi. 10.1002/eji.202250339
By:
- Krenzlin, Viola;
- Schöche, Johannes;
- Walachowski, Sarah;
- Reinhardt, Christoph;
- Radsak, Markus P.;
- Bosmann, Markus
Publication type:
Article
Transcutaneous immunization with CD40 ligation boosts cytotoxic T lymphocyte mediated antitumor immunity independent of CD4 helper cells in mice.
Published in:
European Journal of Immunology, 2019, v. 49, n. 11, p. 2083, doi. 10.1002/eji.201848039
By:
- Bialojan, Ariane;
- Sohl, Julian;
- Rausch, Johanna;
- Aranda Lopez, Pamela;
- Denny, Mark;
- Langguth, Peter;
- Hartmann, Ann‐Kathrin;
- Yagita, Hideo;
- Probst, Hans Christian;
- Schild, Hansjörg;
- Radsak, Markus P.
Publication type:
Article
Donor and host B cell-derived IL-10 contributes to suppression of graft-versus-host disease.
Published in:
European Journal of Immunology, 2014, v. 44, n. 6, p. 1857, doi. 10.1002/eji.201344081
By:
- Weber, Michael;
- Stein, Pamela;
- Prüfer, Steve;
- Rudolph, Berenice;
- Kreft, Andreas;
- Schmitt, Edgar;
- Bopp, Tobias;
- Roers, Axel;
- Schild, Hansjörg;
- Fillatreau, Simon;
- Radsak, Markus P.
Publication type:
Article
Quality by Design (QbD) Approach for a Nanoparticulate Imiquimod Formulation as an Investigational Medicinal Product.
Published in:
Pharmaceutics, 2023, v. 15, n. 2, p. 514, doi. 10.3390/pharmaceutics15020514
By:
- Pielenhofer, Jonas;
- Meiser, Sophie Luise;
- Gogoll, Karsten;
- Ciciliani, Anna-Maria;
- Denny, Mark;
- Klak, Michael;
- Lang, Berenice M.;
- Staubach, Petra;
- Grabbe, Stephan;
- Schild, Hansjörg;
- Radsak, Markus P.;
- Spahn-Langguth, Hilde;
- Langguth, Peter
Publication type:
Article
Current insights into neutrophil homeostasis.
Published in:
Annals of the New York Academy of Sciences, 2012, v. 1266, n. 1, p. 171, doi. 10.1111/j.1749-6632.2012.06607.x
By:
- Bugl, Stefanie;
- Wirths, Stefan;
- Müller, Martin R.;
- Radsak, Markus P.;
- Kopp, Hans‐Georg
Publication type:
Article
ADAMTS-13 regulates neutrophil recruitment in a mouse model of invasive pulmonary aspergillosis.
Published in:
Scientific Reports, 2017, v. 7, n. 1, p. 1, doi. 10.1038/s41598-017-07340-3
By:
- Alflen, Astrid;
- Prüfer, Steve;
- Ebner, Katharina;
- Reuter, Sebastian;
- Aranda Lopez, Pamela;
- Scharrer, Inge;
- Banno, Fumiaki;
- Stassen, Michael;
- Schild, Hansjörg;
- Jurk, Kerstin;
- Bosmann, Markus;
- Beckert, Hendrik;
- Radsak, Markus P.
Publication type:
Article
Physical activity specifically evokes release of cell-free DNA from granulocytes thereby affecting liquid biopsy.
Published in:
Clinical Epigenetics, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13148-022-01245-3
By:
- Neuberger, Elmo W. I.;
- Sontag, Stephanie;
- Brahmer, Alexandra;
- Philippi, Keito F. A.;
- Radsak, Markus P.;
- Wagner, Wolfgang;
- Simon, Perikles
Publication type:
Article
Efficacy of Imiquimod-Based Transcutaneous Immunization Using a Nano-Dispersed Emulsion Gel Formulation.
Published in:
PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0102664
By:
- Stein, Pamela;
- Gogoll, Karsten;
- Tenzer, Stefan;
- Schild, Hansjörg;
- Stevanovic, Stefan;
- Langguth, Peter;
- Radsak, Markus P.
Publication type:
Article
Mechanisms of Cyclic Nucleotide Phosphodiesterases in Modulating T Cell Responses in Murine Graft-versus-Host Disease.
Published in:
PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0058110
By:
- Weber, Michael;
- Lupp, Corinna;
- Stein, Pamela;
- Kreft, Andreas;
- Bopp, Tobias;
- Wehler, Thomas C.;
- Schmitt, Edgar;
- Schild, Hansjörg;
- Radsak, Markus P.
Publication type:
Article
A Role for Toll-Like Receptor Mediated Signals in Neutrophils in the Pathogenesis of the Anti- Phospholipid Syndrome.
Published in:
PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0042176
By:
- Gladigau, Gerd;
- Haselmayer, Philipp;
- Scharrer, Inge;
- Munder, Markus;
- Prinz, Nadine;
- Lackner, Karl;
- Schild, Hansjörg;
- Stein, Pamela;
- Radsak, Markus P.
Publication type:
Article
Regulatory T Cells and IL-10 Independently Counterregulate Cytotoxic T Lymphocyte Responses Induced by Transcutaneous Immunization.
Published in:
PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0027911
By:
- Stein, Pamela;
- Weber, Michael;
- Prüfer, Steve;
- Schmid, Beate;
- Schmitt, Edgar;
- Probst, Hans-Christian;
- Waisman, Ari;
- Langguth, Peter;
- Schild, Hansjörg;
- Radsak, Markus P.
Publication type:
Article
Diagnostic value of sTREM-1, IL-8, PCT, and CRP in febrile neutropenia after autologous stem cell transplantation.
Published in:
2017
By:
- Michel, C.;
- Teschner, D.;
- Wagner, E.;
- Theobald, M.;
- Radsak, Markus;
- Michel, C S;
- Wagner, E M;
- Radsak, Markus P
Publication type:
journal article
Microneedle-enhanced drug delivery: fabrication, characterization, and insights into release and permeation of nanocrystalline imiquimod.
Published in:
Frontiers in Drug Delivery, 2024, p. 1, doi. 10.3389/fddev.2024.1425144
By:
- Meiser, Sophie Luise;
- Pielenhofer, Jonas;
- Hartmann, Ann-Kathrin;
- Stein, Lara;
- Dettweiler, Jule;
- Grabbe, Stephan;
- Radsak, Markus P.;
- Langguth, Peter
Publication type:
Article
Current Progress in Particle-Based Systems for Transdermal Vaccine Delivery.
Published in:
Frontiers in Immunology, 2020, p. 1, doi. 10.3389/fimmu.2020.00266
By:
- Pielenhofer, Jonas;
- Sohl, Julian;
- Windbergs, Maike;
- Langguth, Peter;
- Radsak, Markus P.
Publication type:
Article
Pharmacological degradation of ATR induces antiproliferative DNA replication stress in leukemic cells.
Published in:
Molecular Oncology, 2024, v. 18, n. 8, p. 1958, doi. 10.1002/1878-0261.13638
By:
- Kansy, Anita G.;
- Ashry, Ramy;
- Mustafa, Al‐Hassan M.;
- Alfayomy, Abdallah M.;
- Radsak, Markus P.;
- Zeyn, Yanira;
- Bros, Matthias;
- Sippl, Wolfgang;
- Krämer, Oliver H.
Publication type:
Article
Author Correction: Dithranol as novel co-adjuvant for non-invasive dermal vaccination.
Published in:
2023
By:
- Sohl, Julian;
- Hartmann, Ann-Kathrin;
- Hahlbrock, Jennifer;
- Bartneck, Joschka;
- Stassen, Michael;
- Klein, Matthias;
- Bros, Matthias;
- Grabbe, Stephan;
- Marini, Federico;
- Woods, Kevin;
- Guezguez, Borhane;
- Mack, Matthias;
- Schild, Hansjörg;
- Muth, Sabine;
- Melchior, Felix;
- Probst, Hans Christian;
- Langguth, Peter;
- Radsak, Markus P.
Publication type:
Correction Notice
Prognostic factors and outcome of adult allogeneic hematopoietic stem cell transplantation patients admitted to intensive care unit during transplant hospitalization.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-56322-0
By:
- Michel, Christian S.;
- Teschner, Daniel;
- Schmidtmann, Irene;
- Theobald, Matthias;
- Hauptrock, Beate;
- Wagner-Drouet, Eva M.;
- Radsak, Markus P.
Publication type:
Article
Optimized dithranol-imiquimod-based transcutaneous immunization enables tumor rejection.
Published in:
Frontiers in Immunology, 2023, p. 01, doi. 10.3389/fimmu.2023.1238861
By:
- Hartmann, Ann-Kathrin;
- Bartneck, Joschka;
- Pielenhofer, Jonas;
- Meiser, Sophie Luise;
- Arnold-Schild, Danielle;
- Klein, Matthias;
- Stassen, Michael;
- Schild, Hansjörg;
- Muth, Sabine;
- Probst, Hans Christian;
- Langguth, Peter;
- Grabbe, Stephan;
- Radsak, Markus P.
Publication type:
Article
Efficacy and Safety of Single-Agent Quizartinib, a Potent and Selective FLT3 Inhibitor (FLT3i), in Patients (pts) With FLT3-Internal Tandem Duplication (FLT3-ITD) – Mutated Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML) Enrolled in the Global, Phase 3, Randomized Controlled QuANTUM-R Trial
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2019, v. 19, p. S221, doi. 10.1016/j.clml.2019.07.097
By:
- Jonas, Brian A.;
- Cortes, Jorge E.;
- Khaled, Samer K.;
- Martinelli, Giovanni;
- Perl, Alexander E.;
- Ganguly, Siddhartha;
- Russell, Nigel H.;
- Krämer, Alwin;
- Dombret, Hervé;
- Hogge, Donna;
- Leung, Anskar Y.-H.;
- Mehta, Priyanka;
- Montesinos, Pau;
- Radsak, Markus P.;
- Sica, Simona;
- Arunachalam, Meena;
- Holmes, Melissa;
- Kobayashi, Ken;
- Namuyinga, Ruth;
- Ge, Nanxiang
Publication type:
Article
Herpes virus entry mediator synergizes with Toll-like receptor mediated neutrophil inflammatory responses.
Published in:
Immunology, 2006, v. 119, n. 3, p. 404, doi. 10.1111/j.1365-2567.2006.02449.x
By:
- Haselmayer, Philipp;
- Tenzer, Stefan;
- Kwon, Byoung S.;
- Jung, Gundram;
- Schild, Hansjörg;
- Radsak, Markus P.
Publication type:
Article
UV Exposure Boosts Transcutaneous Immunization and Improves Tumor Immunity: Cytotoxic T-Cell Priming through the Skin.
Published in:
Journal of Investigative Dermatology, 2011, v. 131, n. 1, p. 211, doi. 10.1038/jid.2010.254
By:
- Stein, Pamela;
- Rechtsteiner, Gerd;
- Warger, Tobias;
- Bopp, Tobias;
- Fuhr, Thorsten;
- Prüfer, Steve;
- Probst, Hans-Christian;
- Stassen, Michael;
- Langguth, Peter;
- Schild, Hansjörg;
- Radsak, Markus P
Publication type:
Article
Cancer immunoediting by GITR (glucocorticoid-induced TNF-related protein) ligand in humans: NK cell/tumor cell interactions.
Published in:
FASEB Journal, 2007, v. 21, n. 10, p. 2442, doi. 10.1096/fj.06-7724com
By:
- Baltz, Katrin M.;
- Krusch, Matthias;
- Bringmann, Anita;
- Brossart, Peter;
- Mayer, Frank;
- Kloss, Mercedes;
- Baessler, Tina;
- Kumbier, Ingrid;
- Peterfi, Andrea;
- Kupka, Susan;
- Kroeber, Stefan;
- Menzel, Dagmar;
- Radsak, Markus P.;
- Rammensee, Hans-Georg;
- Salih, Helmut R.
Publication type:
Article
Dithranol as novel co-adjuvant for non-invasive dermal vaccination.
Published in:
NPJ Vaccines, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41541-022-00530-9
By:
- Sohl, Julian;
- Hartmann, Ann-Kathrin;
- Hahlbrock, Jennifer;
- Bartneck, Joschka;
- Stassen, Michael;
- Klein, Matthias;
- Bros, Matthias;
- Grabbe, Stephan;
- Marini, Federico;
- Woods, Kevin;
- Guezguez, Borhane;
- Mack, Matthias;
- Schild, Hansjörg;
- Muth, Sabine;
- Melchior, Felix;
- Probst, Hans Christian;
- Langguth, Peter;
- Radsak, Markus P.
Publication type:
Article
Deletion of Cd44 Inhibits Metastasis Formation of Liver Cancer in Nf2 -Mutant Mice.
Published in:
Cells (2073-4409), 2023, v. 12, n. 9, p. 1257, doi. 10.3390/cells12091257
By:
- Gerardo-Ramírez, Monserrat;
- Giam, Vanessa;
- Becker, Diana;
- Groth, Marco;
- Hartmann, Nils;
- Morrison, Helen;
- May-Simera, Helen L.;
- Radsak, Markus P.;
- Marquardt, Jens U.;
- Galle, Peter R.;
- Herrlich, Peter;
- Straub, Beate K.;
- Hartmann, Monika
Publication type:
Article
Hybrid Biopolymer and Lipid Nanoparticles with Improved Transfection Efficacy for mRNA.
Published in:
Cells (2073-4409), 2020, v. 9, n. 9, p. 2034, doi. 10.3390/cells9092034
By:
- Siewert, Christian D.;
- Haas, Heinrich;
- Cornet, Vera;
- Nogueira, Sara S.;
- Nawroth, Thomas;
- Uebbing, Lukas;
- Ziller, Antje;
- Al-Gousous, Jozef;
- Radulescu, Aurel;
- Schroer, Martin A.;
- Blanchet, Clement E.;
- Svergun, Dmitri I.;
- Radsak, Markus P.;
- Sahin, Ugur;
- Langguth, Peter
Publication type:
Article
Distinct Signaling Cascades of TREM-1, TLR and NLR in Neutrophils and Monocytic Cells.
Published in:
Journal of Innate Immunity, 2014, v. 6, n. 3, p. 339, doi. 10.1159/000355892
By:
- Prüfer, Steve;
- Weber, Michael;
- Sasca, Daniel;
- Teschner, Daniel;
- Wölfel, Catherine;
- Stein, Pamela;
- Stassen, Michael;
- Schild, Hansjörg;
- Radsak, Markus P.
Publication type:
Article
Signaling Pathways of the TREM-1- and TLR4-Mediated Neutrophil Oxidative Burst.
Published in:
Journal of Innate Immunity, 2009, v. 1, n. 6, p. 582, doi. 10.1159/000231973
By:
- Haselmayer, Philipp;
- Daniel, Martin;
- Tertilt, Christine;
- Salih, Helmut R.;
- Stassen, Michael;
- Schild, Hansjörg;
- Radsak, Markus P.
Publication type:
Article
Soluble Triggering Receptor Expressed on Myeloid Cells 1 Is Released in Patients with Stable Chronic Obstructive Pulmonary Disease.
Published in:
Clinical & Developmental Immunology, 2007, p. 1, doi. 10.1155/2007/52040
By:
- Radsak, Markus P.;
- Taube, Christian;
- Haselmayer, Philipp;
- Tenzer, Stefan;
- Salih, Helmut R.;
- RainerWiewrodt;
- Buhl, Roland;
- Schild, Hansjörg
Publication type:
Article
Xenograft models for undifferentiated pleomorphic sarcoma not otherwise specified are essential for preclinical testing of therapeutic agents.
Published in:
Oncology Letters, 2016, v. 12, n. 2, p. 1257, doi. 10.3892/ol.2016.4784
By:
- BECKER, MARC;
- GRAF, CLAUDINE;
- TONAK, MARCUS;
- RADSAK, MARKUS P.;
- BOPP, TOBIAS;
- BALS, ROBERT;
- BOHLE, RAINER M.;
- THEOBALD, MATTHIAS;
- ROMMENS, POL-MARIA;
- PROSCHEK, DIRK;
- WEHLER, THOMAS C.
Publication type:
Article
Author Correction: ADAMTS-13 regulates neutrophil recruitment in a mouse model of invasive pulmonary aspergillosis.
Published in:
Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-32187-7
By:
- Alflen, Astrid;
- Prüfer, Steve;
- Ebner, Katharina;
- Reuter, Sebastian;
- Lopez, Pamela Aranda;
- Scharrer, Inge;
- Banno, Fumiaki;
- Stassen, Michael;
- Schild, Hansjörg;
- Jurk, Kerstin;
- Bosmann, Markus;
- Beckert, Hendrik;
- Radsak, Markus P.
Publication type:
Article
Levels of Soluble Triggering Receptor Expressed on Myeloid Cells 1 in Infectious Exacerbations of Chronic Obstructive Pulmonary Disease.
Published in:
Respiration, 2012, v. 83, n. 2, p. 133, doi. 10.1159/000328413
By:
- Rohde, Gernot;
- Radsak, Markus P.;
- Borg, Irmgard;
- Buhl, Roland;
- Schultze-Werninghaus, Gerhard;
- Taube, Christian
Publication type:
Article
Precursor frequency can compensate for lower TCR expression in T cell competition during priming in vivo.
Published in:
European Journal of Immunology, 2006, v. 36, n. 10, p. 2613, doi. 10.1002/eji.200636331
By:
- Rechtsteiner, Gerd;
- Warger, Tobias;
- Hofmann, Matthias;
- Rammensee, Hans-Georg;
- Schild, Hansjörg;
- Radsak, Markus P.
Publication type:
Article

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