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- Title
Image quality evaluation of iterative model reconstruction on low tube voltage (80 kVp) coronary CT angiography in an animal study.
- Authors
Hu, Mao-Qing; Li, Meng; Liu, Zai-Yi; Huang, Mei-Ping; Liu, Hui; Liang, Chang-Hong
- Abstract
<bold>Background: </bold>Iterative model reconstruction (IMR) is a newer generation iterative reconstruction method, but its value on coronary computed tomography (CT) angiography requires investigation.<bold>Purpose: </bold>To evaluate coronary image quality using IMR at a low-tube voltage of 80 kVp on coronary CT angiography in miniature pigs.<bold>Material and Methods: </bold>Five healthy miniature pigs underwent prospective electrocardiogram-gated coronary 256-slice CT angiography at 120 kVp and 80 kVp tube voltages, respectively. Filtered back projection (FBP) was used to reconstruct the 120 kVp standard-dose (SD) image sets (SD-FBP group), while iDose(4) and IMR were used to reconstruct the 80 kVp low-dose (LD) image sets (LD-iDose(4) and LD-IMR groups). Objective and subjective image qualities were compared among three groups.<bold>Results: </bold>There were no significant differences in mean CT values of the ascending aorta, left main coronary artery, and right coronary artery between the LD-IMR and LD-iDose(4) groups (P > 0.05), but the values were significantly lower in the SD-FBP group than in those two groups (P < 0.05). The image noise in the LD-IMR group (21.5 ± 3.9 HU) was significantly lower than in the LD-iDose(4) (63.7 ± 9.8 HU) and SD-FBP (50.6 ± 4.6 HU) groups (P < 0.05). The signal-to-noise and contrast-to-noise ratios were significantly higher in the LD-IMR group than in the LD-iDose(4) and SD-FBP groups, respectively (P < 0.05). Subjective scoring of image noise, streak artifacts, and overall image quality indicated that the LD-IMR group was consistently superior to the LD-iDose(4) and SD-FBP groups (P < 0.05).<bold>Conclusion: </bold>IMR can significantly improve image quality at a low-tube voltage (80 kVp) with a 66% radiation dose reduction on coronary 256-slice CT angiography in miniature pigs.
- Subjects
CORONARY angiography; COMPUTED tomography; CORONARY artery bypass; MINIATURE pigs; IMAGE quality in imaging systems; ANIMAL models in research; ANIMAL experimentation; BIOLOGICAL models; DIAGNOSTIC imaging; ELECTROCARDIOGRAPHY; LONGITUDINAL method; COMPUTERS in medicine; RESEARCH evaluation; SWINE
- Publication
Acta Radiologica, 2016, Vol 57, Issue 2, p170
- ISSN
0284-1851
- Publication type
journal article
- DOI
10.1177/0284185114568909