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- Title
Experimentally Induced Alterations in Periapical Tissues of the Cat.
- Authors
TORABINEJAD, MAHMOUD; KIGER, ROBERT D.
- Abstract
Ten cats were immunized with subcutaneous injections of keyhole limpet hemocyanin (KLH). After it was determined that the experimental animals had developed circulating antibodies to KLH, challenge doses of KLH were administered via the root canal system. The radiographic and histologic findings suggest that antigen-antibody complex reactions can occur in periapical tissues of teeth, and that they can play a role in the pathogenesis of periapical lesions. In contrast, no radiographic and histologic changes were noted in non-immunized cats.
- Subjects
PERIAPICAL diseases; CATS as laboratory animals; FISSURELLIDAE; HEMOCYANIN; IMMUNOGLOBULINS; ANTIGEN-antibody reactions
- Publication
Journal of Dental Research, 1980, Vol 59, Issue 1, p87
- ISSN
0022-0345
- Publication type
Article
- DOI
10.1177/00220345800590011601