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- Title
Toxicity assessment and heavy metal components of inhalable particulate matters (PM2.5 & PM10) during a dust storm invading the city.
- Authors
Zhang, Dong; Li, Hanhan; Luo, Xiao-San; Huang, Weijie; Pang, Yuting; Yang, Jinshan; Tang, Mingwei; Mehmood, Tariq; Zhao, Zhen
- Abstract
Dust storm (DS) represent global air pollution and health issues considering the high morbidity and premature death rate every year. This study explores the characteristics, composition, and variations in inhalable particulate matters (PMs) as well as their corresponding in vitro toxicity to human lung epithelial cells (A549) during DS and normal days (ND) in the downtown (DT) and the north suburban (NS) of Nanjing city, eastern China. Results showed that compared to ND, concentrations of heavy metals (i.e., Cr, Cu, Ni, and Pb) bound in PMs were lower during the DS. Furthermore, the relationship of cytotoxicity with Ni and Pb levels in PMs was significant. However, the cytotoxicity difference was insignificant between NS and DT. This may be due to the long-range transport of components from natural sources mixed with local pollutants emitted from anthropogenic sources, offsetting the pollution difference between urban and suburban areas. During both periods, PM 2.5 toxicity was greater than PM 10 , while the potential of PM 10 to induce proinflammatory cytokines was comparable to PM 2.5. Results suggested that inflammation risk will increase significantly during DS due to a substantial increase in ambient air PM 10 concentration. [Display omitted]
- Subjects
NANJING (Jiangsu Sheng, China); CHINA; HEAVY metal toxicology; PARTICULATE matter; DUST storms; SUBURBS; AIR pollution; EPITHELIAL cells
- Publication
Process Safety & Environmental Protection: Transactions of the Institution of Chemical Engineers Part B, 2022, Vol 162, p859
- ISSN
0957-5820
- Publication type
Article
- DOI
10.1016/j.psep.2022.04.065