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- Title
Menstrual variation of estrogen receptor content in vaginal tissue.
- Authors
Sjöberg, Inga; Rylander, Eva; von Schoultz, Bo; Sjöberg, I; Rylander, E; von Schoultz, B
- Abstract
Estrogen receptor content in vaginal tissue was quantified in 12 healthy female volunteers during the menstrual cycle. Epithelial biopsies were obtained at cycle days 10 and 21 and investigated by a monoclonal enzyme immunoassay. Measurable amounts of estrogen receptors were found in all women at both sampling occasions. In women with an ovulatory menstrual cycle, a significant fall in V-receptor content was recorded during the luteal phase. Structural and functional changes in the vaginal epithelium during the menstrual cycle may be important for the diagnosis and susceptibility to certain viral infections.
- Subjects
PROTEIN analysis; COMPARATIVE studies; ESTRADIOL; LUTEAL phase; RESEARCH methodology; MEDICAL cooperation; MENSTRUAL cycle; PROGESTERONE; RADIOISOTOPES in medical diagnosis; RESEARCH; VAGINA; EVALUATION research
- Publication
Gynecologic & Obstetric Investigation, 1989, Vol 27, Issue 1, p48
- ISSN
0378-7346
- Publication type
journal article
- DOI
10.1159/000293616