We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Evaluation of Pediatric Brain Death and Organ Donation: 10-Year Experience in a Pediatric Intensive Care Unit in Turkey.
- Authors
Ekinci, Faruk; Yıldızdaş, Dinçer; Horoz, Özden Özgür; İncecik, Faruk
- Abstract
Objective: We aimed to investigate the rate of brain death (BD) determinations and organ donations (OD) in our tertiary pediatric intensive care unit (PICU), and to report the data on the demographic pattern and supplementary descriptive data on BD declarations. Methods: The study was designed as a retrospective, single-center, descriptive cohort study. We evaluated all children who were determined to meet the criteria for BD in our tertiary PICU between January 2011 and December 2020. Results: During study period, BD was identified in 24 patients among 225 total deaths (10.7%). Their median age was 85 months (8-214) and the male-to-female ratio was 1 : 1. The most common diagnosis was meningoencephalitis in 25%, followed by traumatic intracranial hemorrhage (16.7%). The median time from admission to PICU until BD diagnosis was 6.5 days. The time from the first BD physical examination to the declaration of BD was 27.5 hours. There was no statistically important difference between donors and non-donors. The apnea test (AT) was the most performed ancillary method (100%), followed by electroencephalogram (EEG) (66.7%), and magnetic resonance angiography or computed tomography angiography (MRA/CTA) (54.2%). Hyperglycemia developed in 79.2% of the cases, and 70.8% developed diabetes insipidus (DI). Five patients (20.8%) were organ donors in study group. In the study, 13 solid organ and 4 tissue transplantations were performed after OD. Conclusion: Awareness of the incidence and etiology may contribute to the timely diagnosis and declaration of brain death, and with the help of good donor care, may help in increasing OD rates in the pediatric population.
- Subjects
TURKEY; INTENSIVE care units; MAGNETIC resonance angiography; CEREBRAL hemorrhage; ELECTROENCEPHALOGRAPHY; HYPERGLYCEMIA; RESEARCH methodology; TIME; PEDIATRICS; RETROSPECTIVE studies; BRAIN death in children; DESCRIPTIVE statistics; ORGAN donation; LONGITUDINAL method; MENINGOENCEPHALITIS; TRANSPLANTATION of organs, tissues, etc.
- Publication
Turkish Archives of Pediatrics, 2021, Vol 56, Issue 6, p638
- ISSN
2757-6256
- Publication type
Article
- DOI
10.5152/TurkArchPediatr.2021.21130