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Phosphatidylthreonine and Lipid-Mediated Control of Parasite Virulence.
Published in:
PLoS Biology, 2015, v. 13, n. 10, p. 1, doi. 10.1371/journal.pbio.1002288
By:
- Arroyo-Olarte, Ruben D.;
- Brouwers, Jos F.;
- Kuchipudi, Arunakar;
- Helms, J. Bernd;
- Biswas, Aindrila;
- Dunay, Ildiko R.;
- Lucius, Richard;
- Gupta, Nishith
Publication type:
Article
Lipid Droplet Motility Increases Following Viral Immune Stimulation.
Published in:
International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 4418, doi. 10.3390/ijms22094418
By:
- Monson, Ebony A.;
- Whelan, Donna R.;
- Helbig, Karla J.;
- Morita, Eiji;
- Helms, J. B. Bernd
Publication type:
Article
Regulation of Functional Protein Aggregation by Multiple Factors: Implications for the Amyloidogenic Behavior of the CAP Superfamily Proteins.
Published in:
International Journal of Molecular Sciences, 2020, v. 21, n. 18, p. 6530, doi. 10.3390/ijms21186530
By:
- Sheng, Jie;
- Olrichs, Nick K.;
- Gadella, Bart M.;
- Kaloyanova, Dora V.;
- Helms, J. Bernd
Publication type:
Article
Identification of potential drugs for treatment of hepatic lipidosis in cats using an in vitro feline liver organoid system.
Published in:
Journal of Veterinary Internal Medicine, 2020, v. 34, n. 1, p. 132, doi. 10.1111/jvim.15670
By:
- Haaker, Maya W.;
- Kruitwagen, Hedwig S.;
- Vaandrager, Arie B.;
- Houweling, Martin;
- Penning, Louis C.;
- Molenaar, Martijn R.;
- Wolferen, Monique E.;
- Oosterhoff, Loes A.;
- Spee, Bart;
- Helms, J. Bernd
Publication type:
Article
LION/web: a web-based ontology enrichment tool for lipidomic data analysis.
Published in:
GigaScience, 2019, v. 8, n. 6, p. 1, doi. 10.1093/gigascience/giz061
By:
- Molenaar, Martijn R;
- Jeucken, Aike;
- Wassenaar, Tsjerk A;
- van de Lest, Chris H A;
- Brouwers, Jos F;
- Helms, J Bernd
Publication type:
Article
Replacement of Retinyl Esters by Polyunsaturated Triacylglycerol Species in Lipid Droplets of Hepatic Stellate Cells during Activation.
Published in:
PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0034945
By:
- Testerink, Nicole;
- Ajat, Mokrish;
- Houweling, Martin;
- Brouwers, Jos F.;
- Pully, Vishnu V.;
- Manen, Henk-Jan van;
- Otto, Cees;
- Helms, J. Bernd;
- Vaandrager, Arie B.
Publication type:
Article
Distinct lipid compositions of two types of human prostasomes.
Published in:
Proteomics, 2013, v. 13, n. 10/11, p. 1660, doi. 10.1002/pmic.201200348
By:
- Brouwers, Jos F.;
- Aalberts, Marian;
- Jansen, Jeroen W. A.;
- van Niel, Guillaume;
- Wauben, Marca H.;
- Stout, Tom A. E.;
- Helms, J. Bernd;
- Stoorvogel, Willem
Publication type:
Article
Quantitative proteomic identification of host factors involved in the Salmonella typhimurium infection cycle.
Published in:
Proteomics, 2011, v. 11, n. 23, p. 4477, doi. 10.1002/pmic.201100224
By:
- Vogels, Mijke W.;
- van Balkom, Bas W. M.;
- Heck, Albert J. R.;
- de Haan, Cornelis A. M.;
- Rottier, Peter J. M.;
- Batenburg, Joseph J.;
- Kaloyanova, Dora V.;
- Helms, J. Bernd
Publication type:
Article
Identification of host factors involved in coronavirus replication by quantitative proteomics analysis.
Published in:
Proteomics, 2011, v. 11, n. 1, p. 64, doi. 10.1002/pmic.201000309
By:
- Vogels, Mijke W.;
- van Balkom, Bas W. M.;
- Kaloyanova, Dora V.;
- Batenburg, Joseph J.;
- Heck, Albert J.;
- Helms, J. Bernd;
- Rottier, Peter J. M.;
- de Haan, Cornelis A. M.
Publication type:
Article
Characterization of acrosin and acrosin binding protein as novel CRISP2 interacting proteins in boar spermatozoa.
Published in:
Andrology, 2023, v. 11, n. 7, p. 1460, doi. 10.1111/andr.13413
By:
- Zhang, Min;
- Chiozzi, Riccardo Zenezini;
- Bromfield, Elizabeth G;
- Heck, Albert JR;
- Helms, J Bernd;
- Gadella, Bart M
Publication type:
Article
Some Lipid Droplets Are More Equal Than Others: Different Metabolic Lipid Droplet Pools in Hepatic Stellate Cells.
Published in:
Lipid Insights, 2017, n. 10, p. 1, doi. 10.1177/1178635317747281
By:
- Molenaar, Martijn R.;
- Vaandrager, Arie B.;
- Helms, J. Bernd
Publication type:
Article
Zinc binding regulates amyloid-like aggregation of GAPR-1.
Published in:
Bioscience Reports, 2019, v. 39, n. 2, p. 1, doi. 10.1042/BSR20182345
By:
- Jie Sheng;
- Olrichs, Nick K.;
- Geerts, Willie J.;
- Xueyi Li;
- Ur Rehman, Ashfaq;
- Gadella, Barend M.;
- Kaloyanova, Dora V.;
- Helms, J. Bernd
Publication type:
Article
Interpreting the lipidome: bioinformatic approaches to embrace the complexity.
Published in:
Metabolomics, 2021, v. 17, n. 6, p. 1, doi. 10.1007/s11306-021-01802-6
By:
- Kyle, Jennifer E.;
- Aimo, Lucila;
- Bridge, Alan J.;
- Clair, Geremy;
- Fedorova, Maria;
- Helms, J. Bernd;
- Molenaar, Martijn R.;
- Ni, Zhixu;
- Orešič, Matej;
- Slenter, Denise;
- Willighagen, Egon;
- Webb-Robertson, Bobbie-Jo M.
Publication type:
Article
Cholesterol loss during glutamate-mediated excitotoxicity.
Published in:
EMBO Journal, 2012, v. 31, n. 7, p. 1764, doi. 10.1038/emboj.2012.31
By:
- Sodero, Alejandro O;
- Vriens, Joris;
- Ghosh, Debapriya;
- Stegner, David;
- Brachet, Anna;
- Pallotto, Marta;
- Sassoè-Pognetto, Marco;
- Brouwers, Jos F;
- Helms, J Bernd;
- Nieswandt, Bernhard;
- Voets, Thomas;
- Dotti, Carlos G
Publication type:
Article
Inhibition of polyploidization in Pten‐deficient livers reduces steatosis.
Published in:
Liver International, 2022, v. 42, n. 11, p. 2442, doi. 10.1111/liv.15384
By:
- Moreno, Eva;
- Matondo, Augustine B.;
- Bongiovanni, Laura;
- van de Lest, Chris H. A.;
- Molenaar, Martijn R.;
- Toussaint, Mathilda J. M.;
- van Essen, Saskia C.;
- Houweling, Martin;
- Helms, J. Bernd;
- Westendorp, Bart;
- de Bruin, Alain
Publication type:
Article
Metal ions and redox balance regulate distinct amyloid-like aggregation pathways of GAPR-1.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-51232-7
By:
- Sheng, Jie;
- Olrichs, Nick K.;
- Geerts, Willie J.;
- Kaloyanova, Dora V.;
- Helms, J. Bernd
Publication type:
Article
ER stress inhibition enhances formation of triacylglcerols and protects endothelial cells from lipotoxicity.
Published in:
Cell Communication & Signaling, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12964-024-01682-y
By:
- Kovacevic, Igor;
- Schmidt, Paula Henriette;
- Kowalski, Annkatrin;
- Helms, Bernd J.;
- Lest, Chris H. A. van de;
- Kluttig, Alexander;
- Posern, Guido
Publication type:
Article
Normothermic Ex Vivo Liver Platform Using Porcine Slaughterhouse Livers for Disease Modeling.
Published in:
Bioengineering (Basel), 2022, v. 9, n. 9, p. 471, doi. 10.3390/bioengineering9090471
By:
- Krüger, Melanie;
- Ruppelt, Alicia;
- Kappler, Benjamin;
- Van Soest, Elke;
- Samsom, Roos Anne;
- Grinwis, Guy C. M.;
- Geijsen, Niels;
- Helms, J. Bernd;
- Stijnen, Marco;
- Kock, Linda M.;
- Rasponi, Marco;
- Kooistra, Hans S.;
- Spee, Bart
Publication type:
Article
Targeting of the Hydrophobic Metabolome by Pathogens.
Published in:
Traffic, 2015, v. 16, n. 5, p. 439, doi. 10.1111/tra.12280
By:
- Helms, J. Bernd;
- Kaloyanova, Dora V.;
- Strating, Jeroen R. P.;
- van Hellemond, Jaap J.;
- van der Schaar, Hilde M.;
- Tielens, Aloysius G. M.;
- van Kuppeveld, Frank J. M.;
- Brouwers, Jos F.
Publication type:
Article
Review Lipids as Targeting Signals: Lipid Rafts and Intracellular Trafficking.
Published in:
Traffic, 2004, v. 5, n. 4, p. 247, doi. 10.1111/j.1600-0854.2004.0181.x
By:
- Helms, J. Bernd;
- Zurzolo, Chiara
Publication type:
Article
Lysophospholipids secreted by splenic macrophages induce chemotherapy resistance via interference with the DNA damage response.
Published in:
Nature Communications, 2014, v. 5, n. 11, p. 5275, doi. 10.1038/ncomms6275
By:
- Houthuijzen, Julia M.;
- Daenen, Laura G. M.;
- Roodhart, Jeanine M. L.;
- Oosterom, Ilse;
- van Jaarsveld, Marijn T. M.;
- Govaert, Klaas M.;
- Smith, Michelle E.;
- Sadatmand, Sahar J.;
- Rosing, Hilde;
- Kruse, Fabian;
- Helms, Bernd J.;
- van Rooijen, Nico;
- Beijnen, Jos H.;
- Haribabu, Bodduluri;
- van de Lest, Chris H. A.;
- Voest, Emile E
Publication type:
Article
Loss of the interferon-γ-inducible regulatory immunity-related GTPase (IRG), Irgm1, causes activation of effector IRG proteins on lysosomes, damaging lysosomal function and predicting the dramatic susceptibility of Irgm1-deficient mice to infection.
Published in:
BMC Biology, 2016, v. 14, p. 1, doi. 10.1186/s12915-016-0255-4
By:
- Maric-Biresev, Jelena;
- Hunn, Julia P.;
- Krut, Oleg;
- Helms, J. Bernd;
- Martens, Sascha;
- Howard, Jonathan C.
Publication type:
Article
Phosphatidylthreonine and Lipid-Mediated Control of Parasite Virulence.
Published in:
PLoS Pathogens, 2015, v. 11, n. 11, p. 1, doi. 10.1371/journal.pbio.1002288
By:
- Arroyo-Olarte, Ruben D.;
- Brouwers, Jos F.;
- Kuchipudi, Arunakar;
- Helms, J. Bernd;
- Biswas, Aindrila;
- Dunay, Ildiko R.;
- Lucius, Richard;
- Gupta, Nishith
Publication type:
Article
The less conserved metal-binding site in human CRISP1 remains sensitive to zinc ions to permit protein oligomerization.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-84926-y
By:
- Sheng, Jie;
- Gadella, Bart M.;
- Olrichs, Nick K.;
- Kaloyanova, Dora V.;
- Helms, J. Bernd
Publication type:
Article
Identification of a candidate therapeutic autophagy-inducing peptide.
Published in:
Nature, 2013, v. 494, n. 7436, p. 201, doi. 10.1038/nature11866
By:
- Shoji-Kawata, Sanae;
- Sumpter, Rhea;
- Leveno, Matthew;
- Campbell, Grant R.;
- Zou, Zhongju;
- Kinch, Lisa;
- Wilkins, Angela D.;
- Sun, Qihua;
- Pallauf, Kathrin;
- MacDuff, Donna;
- Huerta, Carlos;
- Virgin, Herbert W.;
- Helms, J. Bernd;
- Eerland, Ruud;
- Tooze, Sharon A.;
- Xavier, Ramnik;
- Lenschow, Deborah J.;
- Yamamoto, Ai;
- King, David;
- Lichtarge, Olivier
Publication type:
Article
Playing Jekyll and Hyde—The Dual Role of Lipids in Fatty Liver Disease.
Published in:
Cells (2073-4409), 2020, v. 9, n. 10, p. 2244, doi. 10.3390/cells9102244
By:
- Molenaar, Martijn R.;
- Penning, Louis C.;
- Helms, J. Bernd
Publication type:
Article
Hyperlipidaemia elicits an atypical, T helper 1–like CD4<sup>+</sup> T-cell response: a key role for very low-density lipoprotein.
Published in:
European Heart Journal Open, 2023, v. 3, n. 2, p. 1, doi. 10.1093/ehjopen/oead013
By:
- Os, Bram W van;
- Vos, Winnie G;
- Bosmans, Laura A;
- Tiel, Claudia M van;
- Lith, Sanne C;
- Toom, Myrthe S den;
- Beckers, Linda;
- Levels, Johannes H M;
- Wouw, Suzanne A E van;
- Zelcer, Noam;
- Zaal, Esther A;
- Berkers, Celia R;
- Lest, Chris H A van der;
- Helms, J Bernd;
- Weber, Christian;
- Atzler, Dorothee;
- Winther, Menno P J de;
- Baardman, Jeroen;
- Lutgens, Esther
Publication type:
Article
Identification of host factors involved in coronavirus replication by quantitative proteomics analysis.
Published in:
Proteomics - Clinical Applications, 2011, v. 5, n. 7/8, p. 467, doi. 10.1002/prca.201190043
By:
- Vogels, Mijke W.;
- van Balkom, Bas W. M.;
- Kaloyanova, Dora V.;
- Batenburg, Joseph J.;
- Heck, Albert J.;
- Helms, J. Bernd;
- Rottier, Peter J. M.;
- de Haan, Cornelis A. M.
Publication type:
Article
Aberrant hepatic lipid storage and metabolism in canine portosystemic shunts.
Published in:
PLoS ONE, 2017, v. 12, n. 10, p. 1, doi. 10.1371/journal.pone.0186491
By:
- Van den Bossche, Lindsay;
- Schoonenberg, Vivien A. C.;
- Burgener, Iwan A.;
- Penning, Louis C.;
- Schrall, Ingrid M.;
- Kruitwagen, Hedwig S.;
- van Wolferen, Monique E.;
- Grinwis, Guy C. M.;
- Kummeling, Anne;
- Rothuizen, Jan;
- van Velzen, Jeroen F.;
- Stathonikos, Nikolas;
- Molenaar, Martijn R.;
- Helms, Bernd J.;
- Brouwers, Jos F. H. M.;
- Spee, Bart;
- van Steenbeek, Frank G.
Publication type:
Article

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