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- Title
The molecular and cellular basis of iron toxicity in Iron Overload (IO) disorders. Diagnostic and therapeutic approaches.
- Authors
Cabantchik, Zvi Ioav; Sohn, Yan Sung; Breuer, William; Espósito, Breno Pannia
- Abstract
The article focuses on the non-physiological forms of irons in blood plasma and cells which were implicated in tissue iron accumulation and multi-organ iron overload (IO) disorder and toxicity. Topics discussed include the determination of non-transferrin bound iron (NTBI), labile plasma iron (LPI) and labile cell iron (LCI), and the role of LPI in thalassemia intermedia.
- Subjects
BLOOD plasma; BLOOD cells; TOXICOLOGY of iron; TRANSFERRIN; IRON in the blood; BETA-Thalassemia
- Publication
Thalassemia Reports, 2013, Vol 3, Issue 1s, p7
- ISSN
2039-4357
- Publication type
Article
- DOI
10.4081/thal.2013.s1.e3