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Enzalutamide in castration-resistant prostate cancer patients with visceral disease in the liver and/or lung: Outcomes from the randomized controlled phase 3 AFFIRM trial.
Published in:
2017
By:
- Loriot, Yohann;
- Fizazi, Karim;
- Bono, Johann S.;
- Forer, David;
- Hirmand, Mohammad;
- Scher, Howard I.;
- de Bono, Johann S
Publication type:
journal article
Multiparametric bone MRI can improve CT-guided bone biopsy target selection in cancer patients and increase diagnostic yield and feasibility of next-generation tumour sequencing.
Published in:
European Radiology, 2022, v. 32, n. 7, p. 4647, doi. 10.1007/s00330-022-08536-6
By:
- Donners, Ricardo;
- Figueiredo, Ines;
- Tunariu, Nina;
- Blackledge, Matthew;
- Koh, Dow-Mu;
- de la Maza, Maria de los Dolores Fenor;
- Chandran, Khobe;
- de Bono, Johann S.;
- Fotiadis, Nicos
Publication type:
Article
Selective blockade of androgenic steroid synthesis by novel lyase inhibitors as a therapeutic strategy for treating metastatic prostate cancer.
Published in:
BJU International, 2005, v. 96, n. 9, p. 1241, doi. 10.1111/j.1464-410X.2005.05821.x
By:
- Attard, Gerhardt;
- Belldegrun, Arie S.;
- de Bono, Johann S.
Publication type:
Article
The CT flare response of metastatic bone disease in prostate cancer.
Published in:
2011
By:
- Messiou C;
- Cook G;
- Reid AH;
- Attard G;
- Dearnaley D;
- de Bono JS;
- de Souza NM;
- Messiou, Christina;
- Cook, Gary;
- Reid, Alison H M;
- Attard, Gerhardt;
- Dearnaley, David;
- de Bono, Johann S;
- de Souza, Nandita M
Publication type:
journal article
Systematic study of tissue factor expression in solid tumors.
Published in:
Cancer Reports, 2023, v. 6, n. 2, p. 1, doi. 10.1002/cnr2.1699
By:
- de Bono, Johann S.;
- Harris, Jeffrey R.;
- Burm, Saskia M.;
- Vanderstichele, Adriaan;
- Houtkamp, Mischa A.;
- Aarass, Saida;
- Riisnaes, Ruth;
- Figueiredo, Ines;
- Nava Rodrigues, Daniel;
- Christova, Rossitza;
- Olbrecht, Siel;
- Niessen, Hans W. M.;
- Ruuls, Sigrid R.;
- Schuurhuis, Danita H.;
- Lammerts van Bueren, Jeroen J.;
- Breij, Esther C. W.;
- Vergote, Ignace
Publication type:
Article
27-hydroxycholesterol and DNA damage repair: implication in prostate cancer.
Published in:
Frontiers in Oncology, 2024, p. 01, doi. 10.3389/fonc.2023.1251297
By:
- Galvan, Gloria Cecilia;
- Friedrich, Nadine A.;
- Das, Sanjay;
- Daniels, James P.;
- Pollan, Sara;
- Dambal, Shweta;
- Suzuki, Ryusuke;
- Sanders, Sergio E.;
- Sungyong You;
- Hisashi Tanaka;
- Yeon-Joo Lee;
- Wei Yuan;
- de Bono, Johann S.;
- Vasilevskaya, Irina;
- Knudsen, Karen E.;
- Freeman, Michael R.;
- Freedland, Stephen J.
Publication type:
Article
Neutropenia, neutrophilia, and neutrophil–lymphocyte ratio as prognostic markers in patients with metastatic castration-resistant prostate cancer.
Published in:
Therapeutic Advances in Medical Oncology, 2022, p. 1, doi. 10.1177/17588359221100022
By:
- Meisel, Alexander;
- de Wit, Ronald;
- Oudard, Stephane;
- Sartor, Oliver;
- Stenner-Liewen, Frank;
- Shun, Zhenming;
- Foster, Meredith;
- Ozatilgan, Ayse;
- Eisenberger, Mario;
- de Bono, Johann S.
Publication type:
Article
Molecular pathology and prostate cancer therapeutics: from biology to bedside.
Published in:
Journal of Pathology, 2014, v. 232, n. 2, p. 178, doi. 10.1002/path.4272
By:
- Rodrigues, Daniel Nava;
- Butler, Lisa M;
- Estelles, David Lorente;
- de Bono, Johann S
Publication type:
Article
Phase I study of continuous olaparib capsule dosing in combination with carboplatin and/or paclitaxel (Part 1).
Published in:
Investigational New Drugs, 2020, v. 38, n. 4, p. 1117, doi. 10.1007/s10637-019-00856-7
By:
- van der Noll, Ruud;
- Jager, Agnes;
- Ang, Joo Ern;
- Marchetti, Serena;
- Mergui-Roelvink, Marja W. J.;
- Lolkema, Martijn P.;
- de Jonge, Maja J. A.;
- van der Biessen, Diane A.;
- Brunetto, Andre T.;
- Arkenau, Hendrik-Tobias;
- Tchakov, Ilian;
- Beijnen, Jos H.;
- de Bono, Johann S.;
- Schellens, Jan H. M.
Publication type:
Article
Phase I study of intermittent olaparib capsule or tablet dosing in combination with carboplatin and paclitaxel (part 2).
Published in:
Investigational New Drugs, 2020, v. 38, n. 4, p. 1096, doi. 10.1007/s10637-019-00857-6
By:
- van der Noll, Ruud;
- Jager, Agnes;
- Ang, Joo Ern;
- Marchetti, Serena;
- Mergui-Roelvink, Marja W. J.;
- de Bono, Johann S.;
- Lolkema, Martijn P.;
- de Jonge, Maja J. A.;
- van der Biessen, Diane A.;
- Brunetto, Andre T.;
- Arkenau, Hendrik-Tobias;
- Tchakov, Ilian;
- Beijnen, Jos H.;
- De Grève, Jacques;
- Schellens, Jan H. M.
Publication type:
Article
PARP Inhibitors Mechanism of Action and Their Potential Role in the Prevention and Treatment of Cancer.
Published in:
2012
By:
- Basu, Bristi;
- Sandhu, Shahneen K.;
- de Bono, Johann S.
Publication type:
Journal Article
Management of Metastatic Castration-Resistant Prostate Cancer.
Published in:
2012
By:
- Mukherji, Deborah;
- Eichholz, Andrew;
- De Bono, Johann S.
Publication type:
Journal Article
Circulating Tumor Cells Count and Morphological Features in Breast, Colorectal and Prostate Cancer.
Published in:
PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0067148
By:
- Ligthart, Sjoerd T.;
- Coumans, Frank A. W.;
- Bidard, Francois-Clement;
- Simkens, Lieke H. J.;
- Punt, Cornelis J. A.;
- de Groot, Marco R.;
- Attard, Gerhardt;
- de Bono, Johann S.;
- Pierga, Jean-Yves;
- Terstappen, Leon W. M. M.
Publication type:
Article
Multi-Purpose Utility of Circulating Plasma DNA Testing in Patients with Advanced Cancers.
Published in:
PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0047020
By:
- Perkins, Geraldine;
- Yap, Timothy A.;
- Pope, Lorna;
- Cassidy, Amy M.;
- Dukes, Juliet P.;
- Riisnaes, Ruth;
- Massard, Christophe;
- Cassier, Philippe A.;
- Miranda, Susana;
- Clark, Jeremy;
- Denholm, Katie A.;
- Thway, Khin;
- De Castro, David Gonzalez;
- Attard, Gerhardt;
- Molife, L. Rhoda;
- Kaye, Stan B.;
- Banerji, Udai;
- de Bono, Johann S.
Publication type:
Article
Unbiased and Automated Identification of a Circulating Tumour Cell Definition That Associates with Overall Survival.
Published in:
PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0027419
By:
- Ligthart, Sjoerd T.;
- Coumans, Frank A. W.;
- Attard, Gerhardt;
- Cassidy, Amy Mulick;
- Bono, Johann S. de;
- Terstappen, Leon W. M. M.
Publication type:
Article
Visualizing whole-body treatment response heterogeneity using multi-parametric magnetic resonance imaging.
Published in:
Journal of Algorithms & Computational Technology, 2016, v. 10, n. 4, p. 290, doi. 10.1177/1748301816668024
By:
- Blackledge, Matthew D.;
- Rata, Mihaela;
- Tunariu, Nina;
- Dow-Mu Koh;
- George, Angela;
- Zivi, Andrea;
- Lorente, David;
- Attard, Gerhardt;
- de Bono, Johann S.;
- Leach, Martin O.;
- Collins, David J.
Publication type:
Article
Therapy monitoring of skeletal metastases with whole-body diffusion MRI.
Published in:
Journal of Magnetic Resonance Imaging, 2014, v. 39, n. 5, p. 1049, doi. 10.1002/jmri.24548
By:
- Padhani, Anwar R.;
- Makris, Andreas;
- Gall, Peter;
- Collins, David J.;
- Tunariu, Nina;
- Bono, Johann S.
Publication type:
Article
Phase 1 Study of Molibresib (GSK525762), a Bromodomain and Extra-Terminal Domain Protein Inhibitor, in NUT Carcinoma and Other Solid Tumors.
Published in:
JNCI Cancer Spectrum, 2020, v. 4, n. 2, p. 1, doi. 10.1093/jncics/pkz093
By:
- Piha-Paul, Sarina A;
- Hann, Christine L;
- French, Christopher A;
- Cousin, Sophie;
- Braña, Irene;
- Cassier, Phillippe A;
- Moreno, Victor;
- Bono, Johann S de;
- Harward, Sara Duckworth;
- Ferron-Brady, Geraldine;
- Barbash, Olena;
- Wyce, Anastasia;
- Wu, Yuehui;
- Horner, Thierry;
- Annan, Meg;
- Parr, Nigel J;
- Prinjha, Rabinder K;
- Carpenter, Christopher L;
- Hilton, John;
- Hong, David S
Publication type:
Article
Comparative Survival of Asian and White Metastatic Castration-Resistant Prostate Cancer Men Treated With Docetaxel.
Published in:
JNCI Cancer Spectrum, 2020, v. 4, n. 2, p. 1, doi. 10.1093/jncics/pkaa003
By:
- Halabi, Susan;
- Dutta, Sandipan;
- Tangen, Catherine M;
- Rosenthal, Mark;
- Petrylak, Daniel P;
- Thompson, Ian M;
- Chi, Kim N;
- Bono, Johann S De;
- Araujo, John C;
- Logothetis, Christopher;
- Eisenberger, Mario A;
- Quinn, David I;
- Fizazi, Karim;
- Morris, Michael J;
- Higano, Celestia S;
- Tannock, Ian F;
- Small, Eric J;
- Kelly, William Kevin
Publication type:
Article
Targeting the Intrinsic Apoptosis Pathway: A Window of Opportunity for Prostate Cancer.
Published in:
Cancers, 2022, v. 14, n. 1, p. 51, doi. 10.3390/cancers14010051
By:
- Westaby, Daniel;
- Jimenez-Vacas, Juan M.;
- Padilha, Ana;
- Varkaris, Andreas;
- Balk, Steven P.;
- de Bono, Johann S.;
- Sharp, Adam
Publication type:
Article
Value of Early Circulating Tumor Cells Dynamics to Estimate Docetaxel Benefit in Metastatic Castration-Resistant Prostate Cancer (mCRPC) Patients.
Published in:
Cancers, 2021, v. 13, n. 10, p. 2334, doi. 10.3390/cancers13102334
By:
- Lozano, Rebeca;
- Lorente, David;
- Aragon, Isabel M.;
- Romero-Laorden, Nuria;
- Nombela, Paz;
- Mateo, Joaquim;
- Reid, Alison H. M.;
- Cendón, Ylenia;
- Bianchini, Diletta;
- Llacer, Casilda;
- Sandhu, Shahneen K.;
- Sharp, Adam;
- Rescigno, Pasquale;
- Garcés, Teresa;
- Pacheco, Maria I.;
- Flohr, Penelope;
- Massard, Christophe;
- López-Casas, Pedro P.;
- Castro, Elena;
- de Bono, Johann S.
Publication type:
Article
Scanning Electron Microscopy of Circulating Tumor Cells and Tumor-Derived Extracellular Vesicles.
Published in:
Cancers, 2018, v. 10, n. 11, p. 416, doi. 10.3390/cancers10110416
By:
- Nanou, Afroditi;
- Crespo, Mateus;
- Flohr, Penny;
- De Bono, Johann S.;
- Terstappen, Leon W. M. M.
Publication type:
Article
Bench to Bedside Development of [ 18 F]Fluoromethyl-(1,2- 2 H 4)choline ([ 18 F]D4-FCH).
Published in:
Molecules, 2023, v. 28, n. 24, p. 8018, doi. 10.3390/molecules28248018
By:
- Challapalli, Amarnath;
- Barwick, Tara D.;
- Dubash, Suraiya R.;
- Inglese, Marianna;
- Grech-Sollars, Matthew;
- Kozlowski, Kasia;
- Tam, Henry;
- Patel, Neva H.;
- Winkler, Mathias;
- Flohr, Penny;
- Saleem, Azeem;
- Bahl, Amit;
- Falconer, Alison;
- De Bono, Johann S.;
- Aboagye, Eric O.;
- Mangar, Stephen
Publication type:
Article
Abiraterone acetate plus prednisolone for metastatic patients starting hormone therapy: 5‐year follow‐up results from the STAMPEDE randomised trial (NCT00268476).
Published in:
International Journal of Cancer, 2022, v. 151, n. 3, p. 422, doi. 10.1002/ijc.34018
By:
- James, Nicholas D.;
- Clarke, Noel W.;
- Cook, Adrian;
- Ali, Adnan;
- Hoyle, Alex P.;
- Attard, Gerhardt;
- Brawley, Christopher D.;
- Chowdhury, Simon;
- Cross, William R.;
- Dearnaley, David P.;
- de Bono, Johann S.;
- Diaz‐Montana, Carlos;
- Gilbert, Duncan;
- Gillessen, Silke;
- Gilson, Clare;
- Jones, Rob J.;
- Langley, Ruth E.;
- Malik, Zafar I.;
- Matheson, David J.;
- Millman, Robin
Publication type:
Article
Safety, pharmacokinetic, pharmacodynamic and clinical activity of molibresib for the treatment of nuclear protein of the testis carcinoma and other cancers: Results of a Phase I/II open‐label, dose escalation study.
Published in:
International Journal of Cancer, 2022, v. 150, n. 6, p. 993, doi. 10.1002/ijc.33861
By:
- Cousin, Sophie;
- Blay, Jean‐Yves;
- Garcia, Irene Braña;
- de Bono, Johann S.;
- Le Tourneau, Christophe;
- Moreno, Victor;
- Trigo, Jose;
- Hann, Christine L.;
- Azad, Arun A.;
- Im, Seock‐Ah;
- Cassier, Philippe A.;
- French, Christopher A.;
- Italiano, Antoine;
- Keedy, Vicki L.;
- Plummer, Ruth;
- Sablin, Marie‐Paule;
- Hemming, Matthew L.;
- Ferron‐Brady, Geraldine;
- Wyce, Anastasia;
- Khaled, Ahmed
Publication type:
Article
Future directions in the evaluation of c-MET-driven malignancies.
Published in:
Therapeutic Advances in Medical Oncology, 2011, v. 3, n. 1, p. S51, doi. 10.1177/1758834011423540
By:
- de Bono, Johann S.;
- Yap, Timothy A.
Publication type:
Article
c-MET: an exciting new target for anticancer therapy.
Published in:
Therapeutic Advances in Medical Oncology, 2011, v. 3, n. 1, p. S3, doi. 10.1177/1758834011423402
By:
- de Bono, Johann S.;
- Yap, Timothy A.
Publication type:
Article
Multiparametric bone MRI targeting aides lesion selection for CT-guided sclerotic bone biopsies in metastatic castrate resistant prostate cancer.
Published in:
Cancer Imaging, 2023, v. 23, n. 1, p. 1, doi. 10.1186/s40644-023-00644-w
By:
- Donners, Ricardo;
- Figueiredo, Ines;
- Westaby, Daniel;
- Koh, Dow-Mu;
- Tunariu, Nina;
- Carreira, Suzanne;
- de Bono, Johann S.;
- Fotiadis, Nicos
Publication type:
Article
Novel Strategies to Test Biological Hypotheses in Early Drug Development for Advanced Prostate Cancer.
Published in:
Clinical Chemistry, 2013, v. 59, n. 1, p. 75, doi. 10.1373/clinchem.2012.185157
By:
- Ferraldeschi, Roberta;
- Attard, Gerhardt;
- de Bono, Johann S.
Publication type:
Article
Sarcomatoid carcinoma of the prostate: ERG fluorescence in-situ hybridization confirms epithelial origin.
Published in:
Histopathology, 2015, v. 66, n. 6, p. 898, doi. 10.1111/his.12493
By:
- Rodrigues, Daniel Nava;
- Hazell, Steve;
- Miranda, Susana;
- Crespo, Mateus;
- Fisher, Cyril;
- Bono, Johann S;
- Attard, Gerhardt
Publication type:
Article
The promise of circulating tumor cell analysis in cancer management.
Published in:
Genome Biology, 2014, v. 15, n. 8, p. 448, doi. 10.1186/s13059-014-0448-5
By:
- Mateo, Joaquin;
- Gerlinger, Marco;
- Rodrigues, Daniel Nava;
- de Bono, Johann S
Publication type:
Article
Tumour-derived extracellular vesicles in blood of metastatic cancer patients associate with overall survival.
Published in:
2020
By:
- Nanou, Afroditi;
- Miller, M. Craig;
- Zeune, Leonie L.;
- de Wit, Sanne;
- Punt, Cornelis J. A.;
- Groen, Harry J. M.;
- Hayes, Daniel F.;
- de Bono, Johann S.;
- Terstappen, Leon W. M. M.
Publication type:
journal article
Targeted α-Based Treatment of Metastatic Castration-Resistant Prostate Cancer: Revolutionizing Systemic Radiotherapy?
Published in:
Journal of Nuclear Medicine, 2016, v. 57, n. 12, p. 1838, doi. 10.2967/jnumed.116.179887
By:
- Oyen, Wim J. G.;
- de Bono, Johann S.
Publication type:
Article
Preliminary study of the specific endothelin a receptor antagonist zibotentan in combination with docetaxel in patients with metastatic castration-resistant prostate cancer.
Published in:
Prostate, 2011, v. 71, n. 12, p. 1264, doi. 10.1002/pros.21342
By:
- Trump, Donald L.;
- Payne, Heather;
- Miller, Kurt;
- de Bono, Johann S.;
- Stephenson, Joe;
- Burris, Howard A.;
- Nathan, Faith;
- Taboada, Maria;
- Morris, Thomas;
- Hubner, Andreas
Publication type:
Article
A novel, spontaneously immortalized, human prostate cancer cell line, Bob, offers a unique model for pre-clinical prostate cancer studies.
Published in:
Prostate, 2009, v. 69, n. 14, p. 1507, doi. 10.1002/pros.20997
By:
- Attard, Gerhardt;
- Rizzo, Sian;
- Ledaki, Ioanna;
- Clark, Jeremy;
- Reid, Alison H.M.;
- Thompson, Alan;
- Khoo, Vincent;
- de Bono, Johann S.;
- Cooper, Colin S.;
- Hudson, David L.
Publication type:
Article
Tolerability, safety and pharmacokinetics of ridaforolimus in combination with bicalutamide in patients with asymptomatic, metastatic castration-resistant prostate cancer (CRPC)
Published in:
2013
By:
- Meulenbeld, Hielke J;
- de Bono, Johann S;
- Tagawa, Scott T;
- Whang, Young E;
- Li, Xiaoyun;
- Heath, Karl H;
- Zandvliet, Anthe S;
- Ebbinghaus, Scot W;
- Hudes, Gary R;
- de Wit, Ronald
Publication type:
Journal Article
Safety, tolerability, and pharmacokinetics of the anti-IGF-1R monoclonal antibody figitumumab in patients with refractory adrenocortical carcinoma.
Published in:
Cancer Chemotherapy & Pharmacology, 2010, v. 65, n. 4, p. 765, doi. 10.1007/s00280-009-1083-9
By:
- Haluska, Paul;
- Worden, Frank;
- Olmos, David;
- Donghua Yin;
- Schteingart, David;
- Batzel, Gretchen N.;
- Paccagnella, M. Luisa;
- de Bono, Johann S.;
- Gualberto, Antonio;
- Hammer, Gary D.
Publication type:
Article
Phase I and pharmacokinetic study of cisplatin and troxacitabine administered intravenously every 28 days in patients with advanced solid malignancies.
Published in:
Cancer Chemotherapy & Pharmacology, 2009, v. 65, n. 1, p. 167, doi. 10.1007/s00280-009-1020-y
By:
- Chia-Chi Lin;
- Beeram, Muralidhar;
- Rowinsky, Eric K.;
- Takimoto, Chris H.;
- Ng, Chee M.;
- Geyer Jr., Charles E.;
- Denis, Louis J.;
- De Bono, Johann S.;
- Hao, Desiree;
- Tolcher, Anthony W.;
- Rha, Sun-Young;
- Jolivet, Jacques;
- Patnaik, Amita
Publication type:
Article
A phase II, pharmacokinetic, and biologic study of semaxanib and thalidomide in patients with metastatic melanoma.
Published in:
Cancer Chemotherapy & Pharmacology, 2007, v. 59, n. 2, p. 165, doi. 10.1007/s00280-006-0255-0
By:
- Mita, Monica M.;
- Rowinsky, Eric K.;
- Forero, Leonardo;
- Eckhart, S. Gail;
- Izbicka, Elzbieta;
- Weiss, Geoffrey R.;
- Beeram, Muralidhar;
- Mita, Alain C.;
- de Bono, Johann S.;
- Tolcher, Anthony W.;
- Hammond, Lisa A.;
- Simmons, Paul;
- Berg, Kristin;
- Takimoto, Chris;
- Patnaik, Amita
Publication type:
Article
Phenotypic diversity of circulating tumour cells in patients with metastatic castration-resistant prostate cancer.
Published in:
BJU International, 2017, v. 120, n. 5B, p. E30, doi. 10.1111/bju.13631
By:
- McDaniel, Andrew S.;
- Ferraldeschi, Roberta;
- Krupa, Rachel;
- Landers, Mark;
- Graf, Ryon;
- Louw, Jessica;
- Jendrisak, Adam;
- Bales, Natalee;
- Marrinucci, Dena;
- Zafeiriou, Zafeiris;
- Flohr, Penelope;
- Sideris, Spyridon;
- Crespo, Mateus;
- Figueiredo, Ines;
- Mateo, Joaquin;
- de Bono, Johann S.;
- Dittamore, Ryan;
- Tomlins, Scott A.;
- Attard, Gerhardt
Publication type:
Article
Circulating biomarkers of neuroendocrine prostate cancer: an unmet challenge.
Published in:
2017
By:
- Rescigno, Pasquale;
- Rodrigues, Daniel Nava;
- Bono, Johann S.
Publication type:
Editorial
Final quality of life and safety data for patients with metastatic castration-resistant prostate cancer treated with cabazitaxel in the UK Early Access Programme (EAP) ( NCT01254279).
Published in:
BJU International, 2015, v. 116, n. 6, p. 880, doi. 10.1111/bju.13069
By:
- Bahl, Amit;
- Masson, Susan;
- Malik, Zafar;
- Birtle, Alison J.;
- Sundar, Santhanam;
- Jones, Rob J.;
- James, Nicholas D.;
- Mason, Malcolm D.;
- Kumar, Satish;
- Bottomley, David;
- Lydon, Anna;
- Chowdhury, Simon;
- Wylie, James;
- Bono, Johann S.
Publication type:
Article
Prostate radiotherapy for men with metastatic disease: a new comparison in the Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy ( STAMPEDE) trial.
Published in:
BJU International, 2013, v. 111, n. 5, p. 697, doi. 10.1111/bju.12087
By:
- Parker, Christopher C.;
- Sydes, Matthew R.;
- Mason, Malcolm D.;
- Clarke, Noel W.;
- Aebersold, Daniel;
- Bono, Johann S.;
- Dearnaley, David P.;
- Ritchie, Alastair W.S.;
- Russell, J. Martin;
- Thalmann, George;
- Parmar, Mahesh K.B.;
- James, Nicholas D.
Publication type:
Article
Tumor clone dynamics in lethal prostate cancer.
Published in:
Science Translational Medicine, 2014, v. 6, n. 254, p. 1, doi. 10.1126/scitranslmed.3009448
By:
- Carreira, Suzanne;
- Romanel, Alessandro;
- Goodall, Jane;
- Grist, Emily;
- Ferraldeschi, Roberta;
- Miranda, Susana;
- Prandi, Davide;
- Lorente, David;
- Frenel, Jean-Sebastien;
- Pezaro, Carmel;
- Omlin, Aurelius;
- Rodrigues, Daniel Nava;
- Flohr, Penelope;
- Tunariu, Nina;
- de Bono, Johann S.;
- Demichelis, Francesca;
- Attard, Gerhardt
Publication type:
Article
Therapeutics targeting signal transduction for patients with colorectal carcinoma.
Published in:
British Medical Bulletin, 2002, v. 64, n. 1, p. 227, doi. 10.1093/bmb/64.1.227
By:
- De Bono, Johann S.;
- Rowinsky, Eric K.
Publication type:
Article
Utilizing pharmacokinetics/pharmacodynamics modeling to simultaneously examine free CCL2, total CCL2 and carlumab (CNTO 888) concentration time data.
Published in:
Journal of Clinical Pharmacology, 2013, v. 53, n. 10, p. 1020, doi. 10.1002/jcph.140
By:
- Fetterly, Gerald J.;
- Aras, Urvi;
- Meholick, Patricia D.;
- Takimoto, Chris;
- Seetharam, Shobha;
- McIntosh, Thomas;
- de Bono, Johann S.;
- Sandhu, Shahneen K.;
- Tolcher, Anthony;
- Davis, Hugh M.;
- Zhou, Honghui;
- Puchalski, Thomas A.
Publication type:
Article
A first-in-human phase 1 and pharmacological study of TAS-119, a novel selective Aurora A kinase inhibitor in patients with advanced solid tumours.
Published in:
2021
By:
- Robbrecht, Debbie G. J.;
- Lopez, Juanita;
- Calvo, Emiliano;
- He, Xiaomin;
- Hiroshi, Hirai;
- Soni, Nital;
- Cook, Natalie;
- Dowlati, Afshin;
- Fasolo, Angelica;
- Moreno, Victor;
- Eskens, Ferry A. L. M.;
- de Bono, Johann S.
Publication type:
journal article
First-in-human Phase 1 open label study of the BET inhibitor ODM-207 in patients with selected solid tumours.
Published in:
2020
By:
- Ameratunga, Malaka;
- Braña, Irene;
- Bono, Petri;
- Postel-Vinay, Sophie;
- Plummer, Ruth;
- Aspegren, John;
- Korjamo, Timo;
- Snapir, Amir;
- de Bono, Johann S
Publication type:
journal article
Phase 1 trial of the oral AKT inhibitor MK-2206 plus carboplatin/paclitaxel, docetaxel, or erlotinib in patients with advanced solid tumors.
Published in:
Journal of Hematology & Oncology, 2014, v. 7, n. 1, p. 3, doi. 10.1186/1756-8722-7-1
By:
- Rhoda Molife, L.;
- Li Yan;
- Vitfell-Rasmussen, Joanna;
- Zernhelt, Adriane M.;
- Sullivan, Daniel M.;
- Cassier, Philippe A.;
- Eric Chen;
- Biondo, Andrea;
- Tetteh, Ernestina;
- Siu, Lillian L.;
- Patnaik, Amita;
- Papadopoulos, Kyriakos P.;
- De Bono, Johann S.;
- Tolcher, Anthony W.;
- Minton, Susan
Publication type:
Article
Simple prognostic score for metastatic castration-resistant prostate cancer with incorporation of neutrophil-to-lymphocyte ratio.
Published in:
Cancer (0008543X), 2014, v. 120, n. 21, p. 3346, doi. 10.1002/cncr.28890
By:
- Templeton, Arnoud J.;
- Pezaro, Carmel;
- Omlin, Aurelius;
- McNamara, Mairéad G.;
- Leibowitz‐Amit, Raya;
- Vera‐Badillo, Francisco E.;
- Attard, Gerhardt;
- de Bono, Johann S.;
- Tannock, Ian F.;
- Amir, Eitan
Publication type:
Article

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