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- Title
Analytical chemistry: Clamping down on cancer detection.
- Authors
Gorodetskaya, Irina A.; Gorodetsky, Alon A.
- Abstract
The article discusses the study by Shana Kelley and colleagues regarding electrochemical clamp assay for the analysis of cell-free nucleic acids (cfNAs). Topics discussed inclcud the technique called clamp polymerase chain reaction (PCR) which was used for detection of DNA mutations, the ability of electrochemical clamp assay to directly and rapidly detect cancer-implicated mutant cfNA, and the potential of the assay in monitoring and detection of cancer.
- Subjects
KELLEY, Shana; ELECTROCHEMICAL analysis; NUCLEIC acids; POLYMERASE chain reaction; DNA mutational analysis; CANCER diagnosis
- Publication
Nature Chemistry, 2015, Vol 7, Issue 7, p541
- ISSN
1755-4330
- Publication type
Article
- DOI
10.1038/nchem.2290