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- Title
The effects of green tea ingestion over four weeks on atherosclerotic markers.
- Authors
Sung, Heungsup; Min, Won-Ki; Lee, Woochang; Chun, Sail; Park, Hyosoon; Lee, Yong-Wha; Jang, Seongsoo; Lee, Do-Hoon
- Abstract
Background: The objective of this study was to evaluate the effects of green tea ingestion over four weeks on atherosclerotic biological markers. Methods: After a one-week baseline period, 12 healthy male volunteers aged 28–42 years drank 600 mL of green tea dailyfor four weeks. Lipid profile, oxidized low-density lipoprotein (ox-LDL), total antioxidant capacity (TAC), C-reactive protein (CRP) and soluble cell adhesion molecules were measured at baseline and after two and four weeks ingestion of green tea. Results: There was no significantchange in the concentrations of lipid profile, TAC, CRP, soluble intercellular adhesion molecule-1 (sICAM-1), or soluble E-selectin after ingestion of green tea. The levels of ox-LDL and soluble vascular cell adhesion molecule-1 (sVCAM-1) were significantly decreased after four weeks of green tea ingestion (Wilcoxon signed rank test, P=0.006). Conclusions: The results of this study suggest an in vivo anti-oxidative effect for green tea and an influence of green tea on atherosclerotic biological markers. The effect of green tea seen on ox-LDL and sVCAM-1provides a potential mechanism for the cardiovascular benefits of regular ingestion of green tea.
- Subjects
GREEN tea; ABSORPTION (Physiology); PHAGOCYTOSIS; CELL adhesion molecules
- Publication
Annals of Clinical Biochemistry, 2005, Vol 42, Issue 4, p292
- ISSN
0004-5632
- Publication type
Article
- DOI
10.1258/0004563054255597