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- Title
Comparison of estimated human effective dose of Ga- and Tc-labeled bombesin based on distribution data in mice.
- Authors
Shanehsazzadeh, Saeed; Lahooti, Afsaneh; Shirmardi, Seyed; Erfani, Mostafa
- Abstract
This study describes the preparation, biodistribution and absorbed dose prediction of Ga and Tc labeled bombesin (BBN) in human organs, after injection in mice determined via medical internal radiation dose. We estimated that a 185-MBq injection of Ga-BBN into the humans would result in an estimated effective absorbed dose of 2.50 mSv whereas this value for Tc-BBN is 1.33 mSv in the whole body. These results suggest that injection of Ga-BBN would result 2 times higher absorbed dose compare to Tc-BBN.
- Subjects
BOMBESIN; GALLIUM isotopes; THERMAL dosimetry; LABORATORY mice; PREDICTION models
- Publication
Journal of Radioanalytical & Nuclear Chemistry, 2015, Vol 305, Issue 2, p513
- ISSN
0236-5731
- Publication type
Article
- DOI
10.1007/s10967-015-3995-7