We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Low Virulence and Lack of Airborne Transmission of the Dutch Highly Pathogenic Avian Influenza Virus H5N8 in Ferrets.
- Authors
Richard, Mathilde; Herfst, Sander; van den Brand, Judith M. A.; Lexmond, Pascal; Bestebroer, Theo M.; Rimmelzwaan, Guus F.; Koopmans, Marion; Kuiken, Thijs; Fouchier, Ron A. M.
- Abstract
Highly pathogenic avian influenza (HPAI) H5N8 viruses that emerged in poultry in East Asia spread to Europe and North America by late 2014. Here we show that the European HPAI H5N8 viruses differ from the Korean and Japanese HPAI H5N8 viruses by several amino acids and that a Dutch HPAI H5N8 virus had low virulence and was not transmitted via the airborne route in ferrets. The virus did not cross-react with sera raised against pre-pandemic H5 vaccine strains. This data is useful for public health risk assessments.
- Subjects
AVIAN influenza A virus; VIRUS virulence; AIRBORNE infection; FERRET; VIRUS disease transmission; PUBLIC health -- Risk factors; VIRAL vaccines; DISEASES
- Publication
PLoS ONE, 2015, Vol 10, Issue 6, p1
- ISSN
1932-6203
- Publication type
Article
- DOI
10.1371/journal.pone.0129827