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- Title
Autoimmune, inflammatory, allergic and neuropsychiatric outcomes of offspring born to mothers with vitiligo: a nationwide Korean population-based birth cohort study.
- Authors
Han, Ju Hee; Ju, Hyun Jeong; Kang, Hyun; Lee, Ji Hae; Lee, Solam; Bae, Jung Min
- Abstract
A history of maternal autoimmune disease was defined as at least three medical visits for either systemic lupus erythematosus, rheumatoid arthritis, inflammatory bowel disease, alopecia areata, vitiligo or autoimmune thyroiditis. Incidence of childhood-onset vitiligo and increased risk of atopic dermatitis, autoimmune diseases, and psoriasis: a nationwide population-based study. Https://doi.org/10.1093/bjd/ljad196 Dear Editor, Vitiligo is an autoimmune disease characterized by cutaneous patchy depigmentation.[1] In addition to a genetic predisposition, CD8 SP + sp T cells play a critical role in the autoimmune nature of vitiligo.[1] Associations between vitiligo and autoimmune diseases have been reported, and a recent study has shown an increased incidence of autoimmune diseases in childhood-onset vitiligo.[2] Maternal autoimmunity is suggested to be associated with the development of autoimmune diseases in offspring, in addition to allergic and neuropsychiatric disorders.[1],[3],[4] This study analysed a nationwide birth cohort for the risk of autoimmune, allergic and neuropsychiatric outcomes in offspring born to mothers with vitiligo.
- Subjects
VITILIGO; COHORT analysis; MOTHERS; FETAL diseases; NOSOLOGY
- Publication
British Journal of Dermatology, 2023, Vol 189, Issue 4, p488
- ISSN
0007-0963
- Publication type
Article
- DOI
10.1093/bjd/ljad196