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- Title
Trichosporon beigelii: a life-threatening pathogen in immunocompromised hosts.
- Authors
Erer, B; Galimberti, M; Lucarelli, G; Giardini, C; Polchi, P; Baronciani, D; Gaziev, D; Angelucci, E; Izzi, G
- Abstract
Patients undergoing bone marrow transplantation are profoundly immunosuppressed as a result of their intensive myeloablative chemotherapy and are at high risk for opportunistic fungal infections mainly caused by Candida spp and Aspergillus spp. Trichosporon beigelii (T beigelii) has emerged as a life-threatening opportunistic pathogen in granulocytopenic and immunocompromised hosts and there is a marked increase in cases reported in the literature. Response to antifungal agents is poor, mortality is high and immunological recovery is the most important factor for a favorable outcome in patients with trichosporonosis. We present three cases of T. beigelii infection in patients undergoing allogeneic bone marrow transplantation in our center and we review cases described in the literature. Bone Marrow Transplantation (2000) 25, 745–749.
- Subjects
BONE marrow transplantation; IMMUNOSUPPRESSION; PATHOGENIC microorganisms
- Publication
Bone Marrow Transplantation, 2000, Vol 25, Issue 7, p745
- ISSN
0268-3369
- Publication type
Article
- DOI
10.1038/sj.bmt.1702231