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PARP1-SNAI2 transcription axis drives resistance to PARP inhibitor, Talazoparib.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-16623-3
By:
- Ding, Xia;
- Zhu, Zhou;
- Lapek, John;
- McMillan, Elizabeth A.;
- Zhang, Alexander;
- Chung, Chi-Yeh;
- Dubbury, Sara;
- Lapira, Jennifer;
- Firdaus, Sarah;
- Kang, Xiaolin;
- Gao, Jingjin;
- Oyer, Jon;
- Chionis, John;
- Rollins, Robert A.;
- Li, Lianjie;
- Niessen, Sherry;
- Bagrodia, Shubha;
- Zhang, Lianglin;
- VanArsdale, Todd
Publication type:
Article
Combined gemcitabine and CHK1 inhibitor treatment induces apoptosis resistance in cancer stem cell-like cells enriched with tumor spheroids from a non-small cell lung cancer cell line.
Published in:
Frontiers of Medicine, 2013, v. 7, n. 4, p. 462, doi. 10.1007/s11684-013-0270-6
By:
- Fang, Douglas D.;
- Cao, Joan;
- Jani, Jitesh P.;
- Tsaparikos, Konstantinos;
- Blasina, Alessandra;
- Kornmann, Jill;
- Lira, Maruja E.;
- Wang, Jianying;
- Jirout, Zuzana;
- Bingham, Justin;
- Zhu, Zhou;
- Gu, Yin;
- Los, Gerrit;
- Hostomsky, Zdenek;
- VanArsdale, Todd
Publication type:
Article
A versatile drug delivery system targeting senescent cells.
Published in:
EMBO Molecular Medicine, 2018, v. 10, n. 9, p. 1, doi. 10.15252/emmm.201809355
By:
- Muñoz‐Espín, Daniel;
- Rovira, Miguel;
- Galiana, Irene;
- Giménez, Cristina;
- Lozano‐Torres, Beatriz;
- Paez‐Ribes, Marta;
- Llanos, Susana;
- Chaib, Selim;
- Muñoz‐Martín, Maribel;
- Ucero, Alvaro C.;
- Garaulet, Guillermo;
- Mulero, Francisca;
- Dann, Stephen G.;
- VanArsdale, Todd;
- Shields, David J.;
- Bernardos, Andrea;
- Murguía, José Ramón;
- Martínez‐Máñez, Ramón;
- Serrano, Manuel
Publication type:
Article
Multimodal perturbation analyses of cyclin-dependent kinases reveal a network of synthetic lethalities associated with cell-cycle regulation and transcriptional regulation.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-33329-2
By:
- Ford, Kyle;
- Munson, Brenton P.;
- Fong, Samson H.;
- Panwala, Rebecca;
- Chu, Wai Keung;
- Rainaldi, Joseph;
- Plongthongkum, Nongluk;
- Arunachalam, Vinayagam;
- Kostrowicki, Jarek;
- Meluzzi, Dario;
- Kreisberg, Jason F.;
- Jensen-Pergakes, Kristen;
- VanArsdale, Todd;
- Paul, Thomas;
- Tamayo, Pablo;
- Zhang, Kun;
- Bienkowska, Jadwiga;
- Mali, Prashant;
- Ideker, Trey
Publication type:
Article
Palbociclib and Fulvestrant Act in Synergy to Modulate Central Carbon Metabolism in Breast Cancer Cells.
Published in:
Metabolites (2218-1989), 2019, v. 9, n. 1, p. 7, doi. 10.3390/metabo9010007
By:
- Warth, Benedikt;
- Palermo, Amelia;
- Rattray, Nicholas J.W.;
- Lee, Nathan V.;
- Zhu, Zhou;
- Hoang, Linh T.;
- Cai, Yuping;
- Mazurek, Anthony;
- Dann, Stephen;
- VanArsdale, Todd;
- Fantin, Valeria R.;
- Shields, David;
- Siuzdak, Gary;
- Johnson, Caroline H.
Publication type:
Article
Resistance to dual blockade of the kinases PI3K and mTOR in KRAS-mutant colorectal cancer models results in combined sensitivity to inhibition of the receptor tyrosine kinase EGFR.
Published in:
Science Signaling, 2014, v. 7, n. 351, p. 1, doi. 10.1126/scisignal.2005516
By:
- Belmont, Peter J.;
- Ping Jiang;
- McKee, Trevor D.;
- Tao Xie;
- Isaacson, Jason;
- Baryla, Nicole E.;
- Roper, Jatin;
- Sinnamon, Mark J.;
- Lee, Nathan V.;
- Kan, Julie L. C.;
- Guicherit, Oivin;
- Wouters, Bradly G.;
- O'Brien, Catherine A.;
- Shields, David;
- Olson, Peter;
- VanArsdale, Todd;
- Weinrich, Scott L.;
- Rejto, Paul;
- Christensen, James G.;
- Fantin, Valeria R.
Publication type:
Article
Antitumor Efficacy of the Dual PI3K/mTOR Inhibitor PF-04691502 in a Human Xenograft Tumor Model Derived from Colorectal Cancer Stem Cells Harboring a <i>PIK3CA</i> Mutation.
Published in:
PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0067258
By:
- Fang, Douglas D.;
- Zhang, Cathy C.;
- Gu, Yin;
- Jani, Jitesh P.;
- Cao, Joan;
- Tsaparikos, Konstantinos;
- Yuan, Jing;
- Thiel, Melissa;
- Jackson-Fisher, Amy;
- Zong, Qing;
- Lappin, Patrick B.;
- Hayashi, Tomoko;
- Schwab, Richard B.;
- Wong, Anthony;
- John-Baptiste, Annette;
- Bagrodia, Shubha;
- Los, Geritt;
- Bender, Steve;
- Christensen, James;
- VanArsdale, Todd
Publication type:
Article
Apoptosis mediated by the TNF-related cytokine and receptor families.
Published in:
Journal of Cellular Biochemistry, 1996, v. 60, n. 1, p. 47, doi. 10.1002/(SICI)1097-4644(19960101)60:1<47::AID-JCB8>3.0.CO;2-3
By:
- Ware, Carl F.;
- VanArsdale, Sammee;
- VanArsdale, Todd L.
Publication type:
Article
Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia.
Published in:
2009
By:
- Zhao, Chen;
- Chen, Alan;
- Jamieson, Catriona H.;
- Fereshteh, Mark;
- Abrahamsson, Annelie;
- Blum, Jordan;
- Kwon, Hyog Young;
- Kim, Jynho;
- Chute, John P.;
- Rizzieri, David;
- Munchhof, Michael;
- VanArsdale, Todd;
- Beachy, Philip A.;
- Reya, Tannishtha
Publication type:
Correction Notice
Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia.
Published in:
2009
By:
- Zhao, Chen;
- Chen, Alan;
- Jamieson, Catriona H.;
- Fereshteh, Mark;
- Abrahamsson, Annelie;
- Blum, Jordan;
- Kwon, Hyog Young;
- Kim, Jynho;
- Chute, John P.;
- Rizzieri, David;
- Munchhof, Michael;
- VanArsdale, Todd;
- Beachy, Philip A.;
- Reya, Tannishtha
Publication type:
Letter
Real‐World Data of Palbociclib in Combination With Endocrine Therapy for the Treatment of Metastatic Breast Cancer in Men.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 1, p. 302, doi. 10.1002/cpt.2454
By:
- Kraus, Albert L.;
- Yu‐Kite, Michelle;
- Mardekian, Jack;
- Cotter, Matthew J.;
- Kim, Sindy;
- Decembrino, Jaclyn;
- Snow, Tamara;
- Carson, Kenneth R.;
- Motyl Rockland, Jillian;
- Gossai, Anala;
- Wilner, Keith;
- Wang, Diane D.;
- Huang Bartlett, Cynthia;
- Oharu, Norihiko;
- Schnell, Patrick;
- VanArsdale, Todd;
- Lu, Dongrui R.;
- Tursi, Jennifer M.
Publication type:
Article
Cisplatin exposure causes c-Myc-dependent resistance to CDK4/6 inhibition in HPV-negative head and neck squamous cell carcinoma.
Published in:
Cell Death & Disease, 2019, v. 10, n. 11, p. 1, doi. 10.1038/s41419-019-2098-8
By:
- Robinson, Anthony M.;
- Rathore, Richa;
- Redlich, Nathan J.;
- Adkins, Douglas R.;
- VanArsdale, Todd;
- Van Tine, Brian A.;
- Michel, Loren S.
Publication type:
Article
GLI2 inhibition abrogates human leukemia stem cell dormancy.
Published in:
Journal of Translational Medicine, 2015, v. 13, n. 1, p. 1, doi. 10.1186/s12967-015-0453-9
By:
- Sadarangani, Anil;
- Pineda, Gabriel;
- Lennon, Kathleen M.;
- Hye-Jung Chun;
- Alice Shih;
- Schairer, Annelie E.;
- Court, Angela C.;
- Goff, Daniel J.;
- Prashad, Sacha L.;
- Geron, Ifat;
- Wall, Russell;
- McPherson, John D.;
- Moore, Richard A.;
- Minya Pu;
- Lei Bao;
- Jackson-Fisher, Amy;
- Munchhof, Michael;
- VanArsdale, Todd;
- Reya, Tannishtha;
- Morris, Sheldon R.
Publication type:
Article
GLI2 inhibition abrogates human leukemia stem cell dormancy.
Published in:
2015
By:
- Sadarangani, Anil;
- Pineda, Gabriel;
- Lennon, Kathleen M;
- Chun, Hye-Jung;
- Shih, Alice;
- Schairer, Annelie E;
- Court, Angela C;
- Goff, Daniel J;
- Prashad, Sacha L;
- Geron, Ifat;
- Wall, Russell;
- McPherson, John D;
- Moore, Richard A;
- Pu, Minya;
- Bao, Lei;
- Jackson-Fisher, Amy;
- Munchhof, Michael;
- VanArsdale, Todd;
- Reya, Tannishtha;
- Morris, Sheldon R
Publication type:
journal article
Comparative biomarker analysis of PALOMA-2/3 trials for palbociclib.
Published in:
NPJ Precision Oncology, 2022, v. 6, n. 1, p. 1, doi. 10.1038/s41698-022-00297-1
By:
- Zhu, Zhou;
- Turner, Nicholas C.;
- Loi, Sherene;
- André, Fabrice;
- Martin, Miguel;
- Diéras, Véronique;
- Gelmon, Karen A.;
- Harbeck, Nadia;
- Zhang, Cathy;
- Cao, Joan Q.;
- Yan, Zhengming;
- Lu, Dongrui R.;
- Wei, Ping;
- VanArsdale, Todd L.;
- Rejto, Paul A.;
- Huang, Xin;
- Rugo, Hope S.;
- Loibl, Sibylle;
- Cristofanilli, Massimo;
- Finn, Richard S.
Publication type:
Article

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