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- Title
25 YEARS OF ANTIBODY TREATMENTS FOR LYMPHOMA.
- Authors
Johnson, P. M. W.
- Abstract
Keywords: antibody-drug conjugate, antibody therapy, checkpoint-blocking antibody, immunotherapy, lymphoma B No conflicts of interests pertinent to the abstract. b Whilst endogenous antibody effector mechanisms have been behind the largest improvements in clinical results, the use of antibodies to convey radionuclide or cytotoxic payloads has also been an important area of clinical investigation. Starting from the invention of technology to produce monoclonal antibodies in 1978, and the subsequent immunophenotypic characterisation of the molecules expressed on the surface of lymphoid cells, the idea of targeting the malignant cells of lymphoma using specific antibodies held an intuitive appeal.
- Subjects
CANCER treatment; IMMUNOGLOBULINS
- Publication
Hematological Oncology, 2023, Vol 41, p30
- ISSN
0278-0232
- Publication type
Article
- DOI
10.1002/hon.3163_3