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- Title
Comments on: Cervical cancer prevention in El Salvador: A prospective evaluation of screening and triage strategies incorporating high‐resolution microendoscopy to detect cervical precancer.
- Authors
Pretorius, Robert G.; Belinson, Jerome L.
- Abstract
Cervical cancer prevention in El Salvador: a prospective evaluation of screening and triage strategies incorporating high-resolution microendoscopy to detect cervical precancer. Comments on: Cervical cancer prevention in El Salvador: A prospective evaluation of screening and triage strategies incorporating high-resolution microendoscopy to detect cervical precancer We commend the authors for performing a prospective trial to evaluate high-resolution microendoscopy (HRME), human papillomavirus (HPV) testing using careHPV ([QIAGEN, Gaithersberg, MD], a signal-amplification assay that detects 14 different carcinogenic HPV types that can be done in roughly 2-5 hours) and visual inspection with acetic acid (VIA) to detect cervical intraepithelial neoplasia (CIN) 2, CIN 3 or cervical cancer (CIN2+).1 We have concerns with respect to the study methodology, statistical analysis and the use of Proflavine (a fluorescent acridine compound), which was applied to the cervix prior to HRME.
- Subjects
EL Salvador; CANCER prevention; CERVICAL cancer; MEDICAL triage; CONFOCAL fluorescence microscopy
- Publication
International Journal of Cancer, 2021, Vol 149, Issue 4, p967
- ISSN
0020-7136
- Publication type
Article
- DOI
10.1002/ijc.33587