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- Title
Effect of age and sex in renal function by ultrasound and serum chemistry in two primate species (Alouatta caraya and Sapajus apella).
- Authors
da Silva, Gessiane Pereira; de Souza Pereira, Thyago Habner; Imbeloni, Aline Amaral; do Santos de Andrade, Rafael; Dias Neto, Ramiro das Neves; Coutinho, Leandro Nassar; Gering, Ana Paula; Benarrós, Marina Sette Camara; Junior, José Jones Pereira; Monteiro, Frederico Ozanan Barros; Takeshita, Rafaela S. C.
- Abstract
Background: Comparative studies of kidney morphophysiology in nonhuman primates can help us investigate interspecies differences in growth and aging patterns. Methods: We tested the effect of age and sex in renal morphophysiology in 21 Alouatta caraya and 21 Sapajus apella (age range = 0.5–26 years) by ultrasound, red blood cell (RBC) count, and kidney function tests. Results: A. caraya had greater growth rate and absolute renal volume than S. apella, but the latter showed a greater relative renal volume and RBC count. There was a negative relationship between RBC and age, a positive relationship between creatinine and body mass, and an apparent negative relationship between creatinine and age only in S. apella. Conclusions: Our results indicate that A. caraya has a faster aging mechanism than S. apella, and the higher relative kidney volume in S. apella is suggestive of high metabolic demands in this species.
- Subjects
KIDNEY physiology; KIDNEY function tests; ERYTHROCYTES; ULTRASONIC imaging; PRIMATES
- Publication
Journal of Medical Primatology, 2022, Vol 51, Issue 4, p223
- ISSN
0047-2565
- Publication type
Article
- DOI
10.1111/jmp.12599