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- Title
Metastaziranje endometrijskog karcinoma u jajnik ili istodobni primarni karcinomi endometrija i jajnika - prikaz bolesnice.
- Authors
Simon, Suzana Katalenić; Valetić, Josip; Bolanča, Ines Krivak; Škrtić, Anita
- Abstract
Primary endometrial cancer is the most common malignant neoplasm of the female reproductive system. It is most commonly detected in the first stage of the disease. The most frequent initial symptoms are irregular or prolonged bleeding in premenopausal or bleeding in postmenopausal women. Other symptoms are pain in the pelvis or abdomen, or abnormal Pap smear. Patients are most often in postmenopausal period of life but women in generative age are not excluded. Different researches have shown that women of generative age with endometrial cancer have an increased risk of the synchronous disease of ovarian cancer and hereditary non-polypoid colon cancer. This is exactly corroborated by the fact that primary cancer in the reproductive system of women may occur at the same time, especially in endometrial cancer and in ovarian cancer. The entity of the synchronous primary cancer of endometrium and ovary is a large diagnostic trap because there is no unique histological algorithm or unique attitude for surgical procedure. However,, it is necessary to separate this entity from primary ovarian cancer and metastatic endometrial cancer in the ovary because of its better prognosis and possibility for less aggressive surgery in younger patients with preservation of fertility. We present a 49-year-old patient with history data on abundant bleeding and the existence of ovarian cyst. After intense and severe pain, and because of the suspicion of the rupture of the cyst, the emergency laparoscopic surgery was done. Intraoperative cytological analysis raised doubt about malignant process. Intraoperative histological finding was positive for endometrioid malignant process. Operation was converted to laparotomy. Detailed histopathological analysis, complemented with immunohistochemical procedure, diagnosed metastasis of endometrioid adenocarcinoma of endometrium.
- Publication
Lijecnicki Vjesnik, 2019, Vol 141, Issue 9/10, p289
- ISSN
0024-3477
- Publication type
Article
- DOI
10.26800/LV-141-9-10-37