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- Title
XANTHELASMAS OF THE UPPER GASTROINTESTINAL TRACT: THEIR SIGNIFICANCE AND ASSOCIATION WITH DYSLIPIDEMI.
- Authors
Akın, Mete; Ersoy, İsmail Hakkı; Şenol, Altuğ; Aksakal, Gökhan
- Abstract
Objective: The significance of gastrointestinal xanthelasmas (GX) is unclear, although sometimes lesions they may be confused with malignant lesions. The aim of this study is to investigate the relationship between GX, atrophic gastritis, Helicobacter pylori (HP), and dyslipidemia. Material and Method: Upper gastrointestinal endoscopy reports of 8040 patients were evaluated retrospectively. Among them, 20 patients with GX were included into the study and evaluated for endoscopic characteristics, atrophic gastritis, HP infection and serum lipid profiles. The findings were compared with 20 age- and gender-matched control subjects. Results: The prevalence of GX was 0.24% with no gender difference. As compared with the control group, lipid profiles of GX group showed significantly lower HDL-cholesterol (38.50±9.59 vs 48.80±14.80, p=0.01) and total serum-cholesterol levels (mg/dL) (171.70±26.21 vs 194.25±34.84, p=0.032). LDL- cholesterol and triglyceride levels were not related to the presence of GX. GX showed a close relationship with endoscopically determined atrophic gastritis (30.0% vs 5.0%, p=0.03). HP infection and intestinal metaplasia were not signiicantly related with GX. Conclusion: In our serial endoscopy, the prevalence of GX was 0.24% and it showed an increase with age. Dyslipidemia and atrophic gastritis were found to be related to GX. This relation was not observed with HP infection.
- Subjects
XANTHOMA; GASTROINTESTINAL diseases; DYSLIPIDEMIA; GASTRITIS; HELICOBACTER pylori; RETROSPECTIVE studies
- Publication
Nobel Medicus Journal, 2014, Vol 10, Issue 1, p53
- ISSN
1305-2381
- Publication type
Article