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- Title
Different levels of physical activity and risk of developing type 2 diabetes among adults with prediabetes: a population-based cohort study.
- Authors
Yang, Wenchang; Wu, Yuntao; Chen, Yue; Chen, Shuohua; Gao, Xiang; Wu, Shouling; Sun, Liang
- Abstract
Objectives: This study aimed to evaluate the association between different levels of physical activity and risk of developing type 2 diabetes (T2D) mellitus among adults with prediabetes in Chinese population. Methods: This prospective population-based cohort study included 12,424 participants (mean [SD] age, 52.8 [16.8] years; 82.2% men) with prediabetes at 2014 survey of the Kailuan study. Physical activity information was collected through the International Physical Activity Questionnaire-Short Form and categorized by metabolic equivalent (MET) of task as low, moderate, and high. Cox regression models were built to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for associations between physical activity levels and incident T2D. Results: During a median follow-up of 3.6 years, 2,207 (17.8%) participants developed T2D. The incident rate of T2D were 55.83/1000, 35.14/1000, and 39.61/1000 person-years in the low, moderate, and high physical activity level group, respectively. Both moderate (HR 0.57, 95% CI 0.49 to 0.67) and high (HR 0.76, 95% CI 0.66 to 0.89) physical activity levels were associated with lower risks of developing T2D compared to low physical activity level (P for trend < 0.001). The association between high physical activity level and T2D was primarily observed in participants without metabolic syndrome (P for interaction < 0.001). Moreover, participants with moderate or high levels of physical activity had significantly decreased fasting blood glucose levels during follow-up when compared to those with low level (P group*time < 0.001). Conclusion: This study suggested that individuals with prediabetes might benefit from moderate and high levels of physical activity.
- Publication
Nutrition Journal, 2024, Vol 23, Issue 1, p1
- ISSN
1475-2891
- Publication type
Article
- DOI
10.1186/s12937-024-01013-4