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- Title
Identification of a Novel Parvovirus in the Arctic Wolf (Canis lupus arctos).
- Authors
Dai, Ziyuan; Lu, Qiang; Sun, Mingzhong; Chen, Hongmei; Zhu, Rong; Wang, Huiqing
- Abstract
A novel virus, temporarily named "Arctic wolf parvovirus" (AWPV), was discovered in a pharyngeal metagenomic library derived from an Arctic wolf (Canis lupus arctos) in China. The genome sequence was assigned GenBase accession number C_AA071902.1. AWPV has a genome comprised of 4,920 base pairs with a nucleotide composition of 36.4% A, 23.4% T, 18.2% G, and 22.0% C, with a GC content of 40.2%. Its structure resembles parvoviruses, containing two open reading frames: the nonstructural (NS) region encoding replication enzymes and the structural (VP) region encoding capsid protein. Pairwise sequence comparison and phylogenetic analysis suggest AWPV may represent a novel species within the genus Protoparvovirus. This discovery enhances our understanding of mammalian virus ecology and potential future infectious diseases.
- Publication
Polish Journal of Microbiology, 2024, Vol 73, Issue 3, p395
- ISSN
1733-1331
- Publication type
Article
- DOI
10.33073/pjm-2024-035