We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Non-dipping nocturnal blood pressure in psoriasis vulgaris.
- Authors
Bacaksiz, Ahmet; Akif Vatankulu, Mehmet; Sonmez, Osman; Erdogan, Ercan; Tasal, Abdurrahman; Turfan, Murat; Ertas, Gokhan; Sevgili, Emrah; Dizman, Didem; Onsun, Nahide
- Abstract
Background: Psoriasis vulgaris is one of the most prevalent chronic, inflammatory skin disorders. Patients with psoriasis carry an excess risk of hypertension and adverse cardiovascular (CV) events. Blood pressure (BP) has a circadian rhythm characterised with lower values at night. A blunted nocturnal BP decline defined as non-dipping accelerates the development of hypertension and CV diseases. The aim of this study is to evaluate circadian variation of blood pressure in normotensive middle-aged patients with psoriasis vulgaris. Methods: Seventy adult patients with psoriasis vulgaris (group 1) and 70 age and sex-matched healthy individuals (group 2) were included in the study. Ambulatory BP monitoring was performed in all participants over a 24-h period. Non-dippers are defined as those who show a reduction in BP of less than 10 % between the average day and night systolic BP. Results: Although mean 24-h BPs were similar in both groups, night-time BPs were significantly higher in psoriatic patients (115.1 ± 7.7 vs. 109.9 ± 6.0 mmHg and 72.1 ± 7.0 vs. 67.6 ± 5.5 mmHg, respectively; p < 0.05). The non-dipping pattern of BP changes was significantly more common in patients with psoriasis vulgaris compared with the control group (65.9 vs. 34.1 %, p < 0.01). Psoriasis severity and BMI are independent predictors of impaired nocturnal BP regulation. Conclusions: Patients with psoriasis vulgaris had increased nocturnal BP and heart rate. This is the first study to demonstrate a blunted nocturnal BP decrease in normotensive patients with psoriasis.
- Subjects
PSORIASIS; SKIN diseases; BLOOD pressure; AMBULATORY blood pressure monitoring; HYPERTENSION; CARDIOVASCULAR diseases risk factors
- Publication
Wiener Klinische Wochenschrift, 2012, Vol 124, Issue 23/24, p822
- ISSN
0043-5325
- Publication type
Article
- DOI
10.1007/s00508-012-0294-y