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- Title
Epidemiological characteristics of bloodstream infections in patients with different degrees of liver disease.
- Authors
Brandolini, Micaela; Corbella, Marta; Silvestri, Annalisa; Tinelli, Carmine; Albonico, Giulia; Albertini, Riccardo; Ludovisi, Serena; Bruno, Raffaele; Marone, Piero; Minoli, Lorenzo; Seminari, Elena
- Abstract
Observational retrospective study to evaluate the etiology, the outcome and the risk factors of bloodstream infections (BSIs) in patients with liver disease. One hundred and forty-eight BSIs were diagnosed (infection rate: 0.60 per 100 days of hospital stay), 62 BSIs (41.9 %) were associated with Gram-positive bacteria (infection rate: 0.25 per 100 days of hospital stay) and 80 (54.4 %) with Gram-negative bacteria (infection rate: 0.32 per 100 days of hospital stay). Admission-associated mortality was higher in patients with BSI than in those without BSI (20.6 versus 5.0 %, p < 0.001). Patients with cirrhosis had an increased risk to develop a BSI compared with patients with chronic hepatitis, specifically for Gram-positive (and Staphylococcus spp)-related BSI.
- Subjects
BACTEREMIA; CHRONIC diseases; GRAM-negative bacterial diseases; HEPATITIS; CIRRHOSIS of the liver; LIVER diseases; MORTALITY; GRAM-positive bacterial infections; DISEASE complications; DISEASE risk factors
- Publication
Infection, 2015, Vol 43, Issue 5, p561
- ISSN
0300-8126
- Publication type
Article
- DOI
10.1007/s15010-015-0794-6