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- Title
High-pitch computed tomography pulmonary angiography with iterative reconstruction at 80 kVp and 20 mL contrast agent volume.
- Authors
Lu, Guang; Luo, Song; Meinel, Felix; McQuiston, Andrew; Zhou, Chang; Kong, Xiang; Zhao, Yan; Zheng, Ling; Schoepf, U.; Zhang, Long
- Abstract
Objectives: To evaluate the image quality, radiation dose and diagnostic accuracy of 80kVp, high-pitch CT pulmonary angiography (CTPA) with iterative reconstruction using 20 ml of contrast agent. Methods: One hundred patients with suspected pulmonary embolism (PE) were randomly divided into two groups ( n = 50 each; group A, 100 kVp, 1.2 pitch, 60 ml of contrast medium and filtered back projection algorithm; group B, 80 kVp, 2.2 pitch, 20 ml of contrast medium and sinogram affirmed iterative reconstruction). Image quality, diagnostic accuracy and radiation dose were evaluated and compared. Results: Mean CT numbers of pulmonary arteries in group B were higher than those in group A (all P < 0.001). Contrast-to-noise ratio and signal-to-noise ratio of group B were higher than those of group A (both P < 0.001). There was no significant difference in subjective image quality scores between two groups ( P = 0.807). The interobserver agreement was excellent (k = 0.836). There was no significant difference in diagnostic accuracy between the two groups ( P > 0.05). Compared with group A, radiation dose of group B was reduced by 50.3 % ( P < 0.001). Conclusions: High-pitch CTPA at 80 kVp can obtain sufficient image quality in normal-weight individuals with 20 ml of contrast agent and half the radiation dose of a conventional CTPA protocol. Key Points: • CTPA is feasible at 80 kVp using only 20 ml of contrast agent. • High-pitch CTPA at 80 kVp has an effective dose under 1 mSv. • This CTPA protocol can obtain sufficient image quality in normal-weight individuals.
- Subjects
CHEST X rays; CONTRAST media; COMPUTED tomography; DIAGNOSTIC imaging; MEDICAL radiology
- Publication
European Radiology, 2014, Vol 24, Issue 12, p3260
- ISSN
0938-7994
- Publication type
Article
- DOI
10.1007/s00330-014-3365-9