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- Title
Renal oligo- and anhydramnios: cause, course and outcome-a single-center study.
- Authors
Spiro, Judith; Konrad, Martin; Rieger-Fackeldey, Esther; Masjosthusmann, Katja; Amler, Susanne; Klockenbusch, Walter; Schmitz, Ralf
- Abstract
Purpose: To evaluate the outcome of patients with renal oligohydramnios and explore the impact of patient variables on outcome and prognosis. Methods: A retrospective single-center study was conducted analyzing 104 pregnancies complicated by oligohydramnios of renal origin from 2001 to 2011. Statistical analysis was performed to assess the influence of pre- and postnatal data on pregnancy outcome, morbidity and mortality. Results: Prenatal renal diagnoses were as follows: hydronephrosis/megaureter: n = 21 (20.2 %), aberrance in renal form or location: n = 7 (6.7 %), cystic renal disease: n = 28 (26.9 %), renal dysplasia: n = 24 (23.1 %), renal agenesis: n = 42 (30.4 %), posterior urethral valves: n = 11 (10.6 %). Hydronephrosis/megaureter and late onset of oligohydramnios were prognostic factors for fetal survival, whereas renal agenesis and associated anomalies had a negative impact on pregnancy outcome. Prenatal interventions did not improve prognosis. Conclusions: Pregnancies complicated by renal oligohydramnios still have a poor outcome. Careful weighing of prognostic factors is necessary to decide about further therapeutic measures.
- Subjects
KIDNEY diseases; AMNIOTIC liquid; PREGNANCY complications; DYSPLASIA; HEALTH outcome assessment; CYSTIC kidney disease; PHYSIOLOGY
- Publication
Archives of Gynecology & Obstetrics, 2015, Vol 292, Issue 2, p327
- ISSN
0932-0067
- Publication type
Article
- DOI
10.1007/s00404-015-3648-7