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- Title
A rare occurrence of trisomy 18 and trisomy 21 in a dizygotic twin pregnancy.
- Authors
Pelikan, Harold M. P.; Bijlsma, Emilia K.; van Wijngaarden, Willem J.
- Abstract
Case report of a rare combination of a trisomy 18 and 21 in a dizygotic twin pregnancy in a woman with a history of recurrent miscarriage, a neonatal death, no living offspring and Graves disease. Case report and literature search. Only one other report in the literature of a combined trisomy 18 and 21 twin pregnancy was found. The combination of a trisomy 18 and 21 in a dizygotic twin pregnancy is very rare. Despite the high frequency and clinical importance of aneuploidy, very little is known about the factors that may modulate meiotic non-disjunction.
- Subjects
TRISOMY; DOWN syndrome; MULTIPLE pregnancy; HUMAN chromosome abnormalities; ANEUPLOIDY
- Publication
Archives of Gynecology & Obstetrics, 2007, Vol 276, Issue 5, p533
- ISSN
0932-0067
- Publication type
Article
- DOI
10.1007/s00404-007-0378-5