We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
In Vivo Measurements of Cone Photoreceptor Spacing in Myopic Eyes from Images Obtained by an Adaptive Optics Fundus Camera.
- Authors
Yoshiyuki Kitaguchi; Kenichiro Bessho; Tatsuo Yamaguchi; Naoki Nakazawa; Toshifumi Mihashi; Takashi Fujikado
- Abstract
Abstract Purpose To determine the cone spacing in normal and myopic eyes from the images obtained by an adaptive optics (AO) fundus camera. Methods Nineteen eyes of 19 healthy volunteers with a mean ± SD spherical equivalent refractive error of −3.7 ± 3.3 diopters (D) (range, −0.3 to −11.1 D) and a mean axial length of 25.4 ± 1.61 mm (range, 23.4–28.0 mm) were investigated in a prospective cross-sectional study. An AO fundus camera equipped with a liquid crystal phase modulator was used to obtain the images of the photoreceptor mosaic. The spacing between the cones was calculated manually at a retinal locus 2° temporal from the center of the fovea. The magnification of the image was calculated by the axial length measured with an IOL Master. Results The axial length was correlated with the refractive error (Pearson, r = −0.869; P n = 9) was 4.71 ± 0.44 µm, which was significantly greater (P = 0.002) than the 3.90 ± 0.47 µm in the normal and low-myopia groups (−1.1 ± 0.9 D, n = 10). The cone spacing was significantly correlated with the axial length (r = 0.77, P Conclusions The AO fundus camera is capable of acquiring images of the photoreceptors in normal and myopic eyes. The greater spacing between cones in the myopia group is consistent with histological findings. These results suggest that retinal expansion should be considered in addition to Knapp's law when aniseikonia is evaluated in axial myopia. Jpn J Ophthalmol 2007;51:456–461 © Japanese Ophthalmological Society 2007
- Subjects
MYOPIA; REFRACTIVE errors; ADAPTIVE optics; VISION disorders; VISUAL accommodation
- Publication
Japanese Journal of Ophthalmology, 2007, Vol 51, Issue 6, p456
- ISSN
0021-5155
- Publication type
Article
- DOI
10.1007/s10384-007-0477-7