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- Title
神经外科重症监护病房耐万古霉素肠球菌感染的流行特征及危险因素研究
- Authors
曹新建; 王嵘; 王学军; 李晓兴; 吴继伟
- Abstract
Objective: To investigate the epidemiological characteristics and risk factors of vancomycin resistant enterococcus (VRE) infection in intensive care unit (ICU) of department of neurosurgery, and to provide reference for clinical prevention and control. Methods: A total of 420 patients, who underwent surgery in the ICU of department of neurosurgery in Taizhou Hospital of Traditional Chinese Medicine from January 2014 to January 2016, were chosen as subjects. The application of antibiotics before infection in the patients with VRE infection was compared, and univariate and multivariate Logistic regression analysis were used to analyze the risk factors of VRE infection to propose the prevention and control measures. Results: Among the 420 inpatients in ICU, there were 58 cases of VRE infection, accounted for 13.81%. The most common antibiotics used before VRE infection was three generation cephalosporin, accounted for 37.93%, and four generation cephalosporin was least, accounted for 6.90%. Single factor and Logistic regression analysis showed that the ICU hospitalization times⩾ 14 d, indwelling catheters⩾ 14 d, Glasgow Coma Scale (GCS) score<8 and patients infected by VRE nearby were the risk factors of VRE infection(P<0.05). Conclusion: The most common antibiotics used before VRE infection is three generation cephalosporin. ICU hospitalization times⩾ 14 d, indwelling catheters⩾ 14 d, GCS score<8 and patients infected by VRE nearby are the risk factors of VRE infection. Rational use of antibiotics and taking corresponding prevention and control measures are necessary in the clinical practice to reduce the incidence of VRE infection.
- Subjects
VANCOMYCIN resistance; ENTEROCOCCAL infections; INTENSIVE care units; NEUROSURGERY; CEPHALOSPORINS; LOGISTIC regression analysis
- Publication
Progress in Modern Biomedicine, 2018, Vol 18, Issue 14, p2755
- ISSN
1673-6273
- Publication type
Article
- DOI
10.13241/j.cnki.pmb.2018.14.034