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- Title
Interim analysis: A rational approach of decision making in clinical trial.
- Authors
Kumar, Amal; Chakraborty, Bhaswat S.
- Abstract
Interim analysis of especially sizeable trials keeps the decision process free of conflict of interest while considering cost, resources, and meaningfulness of the project. Whenever necessary, such interim analysis can also call for potential termination or appropriate modification in sample size, study design, and even an early declaration of success. Given the extraordinary size and complexity today, this rational approach helps to analyze and predict the outcomes of a clinical trial that incorporate what is learned during the course of a study or a clinical development program. Such approach can also fill the gap by directing the resources toward relevant and optimized clinical trials between unmet medical needs and interventions being tested currently rather than fulfilling only business and profit goals.
- Subjects
MEDICAL decision making; CLINICAL trials; SAMPLE size (Statistics)
- Publication
Journal of Advanced Pharmaceutical Technology & Research, 2016, Vol 7, Issue 4, p118
- ISSN
2231-4040
- Publication type
Article
- DOI
10.4103/2231-4040.191414