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- Title
The Role of Docosahexaenoic Acid (DHA) on Cognitive Functions in Psychiatric Disorders.
- Authors
Ciappolino, Valentina; Mazzocchi, Alessandra; Botturi, Andrea; Turolo, Stefano; Delvecchio, Giuseppe; Agostoni, Carlo; Brambilla, Paolo
- Abstract
Cognitive impairment is strongly associated with functional outcomes in psychiatric patients. Involvement of n-3 long chain polyunsaturated fatty acid (n-3 LC-PUFA), in particular docosahexaenoic acid (DHA), in brain functions is largely documented. DHA is incorporated into membrane phospholipids as structural component, especially in the central nervous system where it also has important functional effects. The aim of this review is to investigate the relationship between DHA and cognitive function in relation to mental disorders. Results from few randomized controlled trials (RCTs) on the effects of DHA (alone or in combination) in psychotic, mood and neurodevelopmental disorders, respectively, suggest that no conclusive remarks can be drawn.
- Subjects
AFFECT (Psychology); CENTRAL nervous system; COGNITION; LIFE skills; MENTAL illness; PHOSPHOLIPIDS; PSYCHOTHERAPY patients; UNSATURATED fatty acids; SYSTEMATIC reviews; DOCOSAHEXAENOIC acid
- Publication
Nutrients, 2019, Vol 11, Issue 4, p769
- ISSN
2072-6643
- Publication type
Article
- DOI
10.3390/nu11040769