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- Title
Potential Antigenic Mismatch of the H3N2 Component of the 2019 Southern Hemisphere Influenza Vaccine.
- Authors
Gouma, Sigrid; Weirick, Madison; Hensley, Scott E
- Abstract
Here, we find that the egg-adapted H3N2 component of the 2019 Southern Hemisphere influenza vaccine elicits an antibody response in ferrets that is highly focused on antigenic site A of hemagglutinin. This is potentially problematic as most H3N2 viruses currently circulating in the Southern Hemisphere possess antigenic site A substitutions.
- Subjects
GENETICS; INFLUENZA vaccines; INFLUENZA A virus, H3N2 subtype
- Publication
Clinical Infectious Diseases, 2020, Vol 70, Issue 11, p2432
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/cid/ciz723