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- Title
Predicting creatinine clearance by a simple formula following live-donor kidney transplantation.
- Authors
C. Zapletal; M. W. Lorenz; G. Woeste; C. Wullstein; M. Golling; W. O. Bechstein
- Abstract
The outcome after live-donor kidney transplantation is influenced by many parameters. The aim of our study was to establish a multivariate prognostic model for calculating the recipient’s creatinine clearance after transplantation. Basic immunological, donor-, recipient- and process-related variables were assessed in a series of 18 live-donor kidney transplant patients with an uncomplicated postoperative course. Multivariate analysis was carried out with automated forward and backward selection. The following four parameters were included in the predictive model: recipient age, recipient BMI, graft clearance and degree of relationship. The coefficient of determination (R 2) was 0.67. It could be shown that a significant prediction of creatinine clearance after living related kidney transplantation can be made, based on simple variables. Therefore, this formula could help to detect early complications in the post-transplantation course if the recipient’s creatinine clearance drops below the predicted result.
- Subjects
KIDNEY transplantation; CREATININE; TRANSPLANTATION of organs, tissues, etc.; MULTIVARIATE analysis
- Publication
Transplant International, 2004, Vol 17, Issue 9, p490
- ISSN
0934-0874
- Publication type
Article
- DOI
10.1111/j.1432-2277.2004.tb00477.x