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Prediction performance and fairness heterogeneity in cardiovascular risk models.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-16615-3
By:
- Kartoun, Uri;
- Khurshid, Shaan;
- Kwon, Bum Chul;
- Patel, Aniruddh P.;
- Batra, Puneet;
- Philippakis, Anthony;
- Khera, Amit V.;
- Ellinor, Patrick T.;
- Lubitz, Steven A.;
- Ng, Kenney
Publication type:
Article
Prediction performance and fairness heterogeneity in cardiovascular risk models.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-16615-3
By:
- Kartoun, Uri;
- Khurshid, Shaan;
- Kwon, Bum Chul;
- Patel, Aniruddh P.;
- Batra, Puneet;
- Philippakis, Anthony;
- Khera, Amit V.;
- Ellinor, Patrick T.;
- Lubitz, Steven A.;
- Ng, Kenney
Publication type:
Article
Cross-modal autoencoder framework learns holistic representations of cardiovascular state.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38125-0
By:
- Radhakrishnan, Adityanarayanan;
- Friedman, Sam F.;
- Khurshid, Shaan;
- Ng, Kenney;
- Batra, Puneet;
- Lubitz, Steven A.;
- Philippakis, Anthony A.;
- Uhler, Caroline
Publication type:
Article
Cross-modal autoencoder framework learns holistic representations of cardiovascular state.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38125-0
By:
- Radhakrishnan, Adityanarayanan;
- Friedman, Sam F.;
- Khurshid, Shaan;
- Ng, Kenney;
- Batra, Puneet;
- Lubitz, Steven A.;
- Philippakis, Anthony A.;
- Uhler, Caroline
Publication type:
Article
BMI-adjusted adipose tissue volumes exhibit depot-specific and divergent associations with cardiometabolic diseases.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-022-35704-5
By:
- Agrawal, Saaket;
- Klarqvist, Marcus D. R.;
- Diamant, Nathaniel;
- Stanley, Takara L.;
- Ellinor, Patrick T.;
- Mehta, Nehal N.;
- Philippakis, Anthony;
- Ng, Kenney;
- Claussnitzer, Melina;
- Grinspoon, Steven K.;
- Batra, Puneet;
- Khera, Amit V.
Publication type:
Article
Inherited basis of visceral, abdominal subcutaneous and gluteofemoral fat depots.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-30931-2
By:
- Agrawal, Saaket;
- Wang, Minxian;
- Klarqvist, Marcus D. R.;
- Smith, Kirk;
- Shin, Joseph;
- Dashti, Hesam;
- Diamant, Nathaniel;
- Choi, Seung Hoan;
- Jurgens, Sean J.;
- Ellinor, Patrick T.;
- Philippakis, Anthony;
- Claussnitzer, Melina;
- Ng, Kenney;
- Udler, Miriam S.;
- Batra, Puneet;
- Khera, Amit V.
Publication type:
Article
Childhood Height Growth Rate Association With the Risk of Islet Autoimmunity and Development of Type 1 Diabetes.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2022, v. 107, n. 6, p. 1520, doi. 10.1210/clinem/dgac121
By:
- Zhiguo Li;
- Veijola, Riitta;
- Koski, Eileen;
- Anand, Vibha;
- Martin, Frank;
- Waugh, Kathleen;
- Hyöty, Heikki;
- Winkler, Christiane;
- Killian, Michael B.;
- Lundgren, Markus;
- Ng, Kenney;
- Maziarz, Marlena;
- Toppari, Jorma
Publication type:
Article
Progression of type 1 diabetes from latency to symptomatic disease is predicted by distinct autoimmune trajectories.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28909-1
By:
- Kwon, Bum Chul;
- Anand, Vibha;
- Achenbach, Peter;
- Dunne, Jessica L.;
- Hagopian, William;
- Hu, Jianying;
- Koski, Eileen;
- Lernmark, Åke;
- Lundgren, Markus;
- Ng, Kenney;
- Toppari, Jorma;
- Veijola, Riitta;
- Frohnert, Brigitte I.;
- the T1DI Study Group
Publication type:
Article
Quantifying the utility of islet autoantibody levels in the prediction of type 1 diabetes in children.
Published in:
Diabetologia, 2023, v. 66, n. 1, p. 93, doi. 10.1007/s00125-022-05799-y
By:
- Ng, Kenney;
- Anand, Vibha;
- Stavropoulos, Harry;
- Veijola, Riitta;
- Toppari, Jorma;
- Maziarz, Marlena;
- Lundgren, Markus;
- Waugh, Kathy;
- Frohnert, Brigitte I.;
- Martin, Frank;
- Lou, Olivia;
- Hagopian, William;
- Achenbach, Peter
Publication type:
Article
Design and user experience testing of a polygenic score report: a qualitative study of prospective users.
Published in:
BMC Medical Genomics, 2021, v. 14, n. 1, p. 1, doi. 10.1186/s12920-021-01056-0
By:
- Brockman, Deanna G.;
- Petronio, Lia;
- Dron, Jacqueline S.;
- Kwon, Bum Chul;
- Vosburg, Trish;
- Nip, Lisa;
- Tang, Andrew;
- O'Reilly, Mary;
- Lennon, Niall;
- Wong, Bang;
- Ng, Kenney;
- Huang, Katherine H.;
- Fahed, Akl C.;
- Khera, Amit V.
Publication type:
Article
Association of the Interaction Between Familial Hypercholesterolemia Variants and Adherence to a Healthy Lifestyle With Risk of Coronary Artery Disease.
Published in:
JAMA Network Open, 2022, v. 5, n. 3, p. e222687, doi. 10.1001/jamanetworkopen.2022.2687
By:
- Fahed, Akl C.;
- Wang, Minxian;
- Patel, Aniruddh P.;
- Ajufo, Ezimamaka;
- Maamari, Dimitri J.;
- Aragam, Krishna G.;
- Brockman, Deanna G.;
- Vosburg, Trish;
- Ellinor, Patrick T.;
- Ng, Kenney;
- Khera, Amit V.
Publication type:
Article
Systematically exploring repurposing effects of antihypertensives.
Published in:
Pharmacoepidemiology & Drug Safety, 2022, v. 31, n. 9, p. 944, doi. 10.1002/pds.5491
By:
- Shahn, Zach;
- Spear, Phoebe;
- Lu, Helen;
- Jiang, Sharon;
- Zhang, Suki;
- Deshmukh, Neil;
- Xu, Shenbo;
- Ng, Kenney;
- Welsch, Roy;
- Finkelstein, Stan
Publication type:
Article
Precision population analytics: population management at the point-of-care.
Published in:
2021
By:
- Tang, Paul C;
- Miller, Sarah;
- Stavropoulos, Harry;
- Kartoun, Uri;
- Zambrano, John;
- Ng, Kenney
Publication type:
journal article
Identifying unreliable predictions in clinical risk models.
Published in:
NPJ Digital Medicine, 2020, v. 3, n. 1, p. 1, doi. 10.1038/s41746-019-0209-7
By:
- Myers, Paul D.;
- Ng, Kenney;
- Severson, Kristen;
- Kartoun, Uri;
- Dai, Wangzhi;
- Huang, Wei;
- Anderson, Frederick A.;
- Stultz, Collin M.
Publication type:
Article
Association of Rare Pathogenic DNA Variants for Familial Hypercholesterolemia, Hereditary Breast and Ovarian Cancer Syndrome, and Lynch Syndrome With Disease Risk in Adults According to Family History.
Published in:
JAMA Network Open, 2020, v. 3, n. 4, p. e203959, doi. 10.1001/jamanetworkopen.2020.3959
By:
- Patel, Aniruddh P.;
- Wang, Minxian;
- Fahed, Akl C.;
- Mason-Suares, Heather;
- Brockman, Deanna;
- Pelletier, Renee;
- Amr, Sami;
- Machini, Kalotina;
- Hawley, Megan;
- Witkowski, Leora;
- Koch, Christopher;
- Philippakis, Anthony;
- Cassa, Christopher A.;
- Ellinor, Patrick T.;
- Kathiresan, Sekar;
- Ng, Kenney;
- Lebo, Matthew;
- Khera, Amit V.
Publication type:
Article
Personalized treatment options for chronic diseases using precision cohort analytics.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-80967-5
By:
- Ng, Kenney;
- Kartoun, Uri;
- Stavropoulos, Harry;
- Zambrano, John A.;
- Tang, Paul C.
Publication type:
Article
The Association of the First Surge of the COVID-19 Pandemic with the High- and Low-Value Outpatient Care Delivered to Adults in the USA.
Published in:
JGIM: Journal of General Internal Medicine, 2022, v. 37, n. 15, p. 3979, doi. 10.1007/s11606-022-07757-1
By:
- Levine, David M.;
- Samal, Lipika;
- Neville, Bridget A.;
- Burdick, Elisabeth;
- Wien, Matthew;
- Rodriguez, Jorge A.;
- Ganesan, Sandya;
- Blitzer, Stephanie C.;
- Yuan, Nina H.;
- Ng, Kenney;
- Park, Yoonyoung;
- Rajmane, Amol;
- Jackson, Gretchen Purcell;
- Lipsitz, Stuart R.;
- Bates, David W.
Publication type:
Article
Exploring the link between Gilbert's syndrome and atherosclerotic cardiovascular disease: insights from a subpopulation-based analysis of over one million individuals.
Published in:
European Heart Journal Open, 2023, v. 3, n. 3, p. 1, doi. 10.1093/ehjopen/oead059
By:
- Kartoun, Uri;
- Fahed, Akl C;
- Kany, Shinwan;
- Singh, Pulkit;
- Khurshid, Shaan;
- Patel, Aniruddh P;
- Batra, Puneet;
- Philippakis, Anthony;
- Khera, Amit V;
- Lubitz, Steven A;
- Ellinor, Patrick T;
- Anand, Vibha;
- Ng, Kenney
Publication type:
Article
Silhouette images enable estimation of body fat distribution and associated cardiometabolic risk.
Published in:
NPJ Digital Medicine, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s41746-022-00654-1
By:
- Klarqvist, Marcus D. R.;
- Agrawal, Saaket;
- Diamant, Nathaniel;
- Ellinor, Patrick T.;
- Philippakis, Anthony;
- Ng, Kenney;
- Batra, Puneet;
- Khera, Amit V.
Publication type:
Article
Deep learning of left atrial structure and function provides link to atrial fibrillation risk.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-48229-w
By:
- Pirruccello, James P.;
- Di Achille, Paolo;
- Choi, Seung Hoan;
- Rämö, Joel T.;
- Khurshid, Shaan;
- Nekoui, Mahan;
- Jurgens, Sean J.;
- Nauffal, Victor;
- Kany, Shinwan;
- FinnGen;
- Ng, Kenney;
- Friedman, Samuel F.;
- Batra, Puneet;
- Lunetta, Kathryn L.;
- Palotie, Aarno;
- Philippakis, Anthony A.;
- Ho, Jennifer E.;
- Lubitz, Steven A.;
- Ellinor, Patrick T.
Publication type:
Article
Analysis of factors associated with extended recovery time after colonoscopy.
Published in:
PLoS ONE, 2018, v. 13, n. 6, p. 1, doi. 10.1371/journal.pone.0199246
By:
- Eschenfeldt, Patrick C.;
- Kartoun, Uri;
- Heberle, Curtis R.;
- Kong, Chung Yin;
- Nishioka, Norman S.;
- Ng, Kenney;
- Kamarthi, Sagar;
- Hur, Chin
Publication type:
Article
Data-Driven Phenotyping of Presymptomatic Type 1 Diabetes Using Longitudinal Autoantibody Profiles.
Published in:
Diabetes Care, 2024, v. 47, n. 8, p. 1424, doi. 10.2337/dc24-0198
By:
- Ghalwash, Mohamed;
- Anand, Vibha;
- Ng, Kenney;
- Dunne, Jessica L.;
- Lou, Olivia;
- Lundgren, Markus;
- Hagopian, William A.;
- Rewers, Marian;
- Ziegler, Anette-G.;
- Veijola, Riitta;
- Ziegler, Anette G.;
- Bonifacio, Ezio;
- Achenbach, Peter;
- Winkler, Christiane;
- Frohnert, Brigitte I.;
- Norris, Jill;
- Steck, Andrea;
- Waugh, Kathleen;
- Yu, Liping;
- Killian, Michael
Publication type:
Article
Refining the Definition of Stage 1 Type 1 Diabetes: An Ontology-Driven Analysis of the Heterogeneity of Multiple Islet Autoimmunity.
Published in:
Diabetes Care, 2023, v. 46, n. 10, p. 1753, doi. 10.2337/dc22-1960
By:
- Frohnert, Brigitte I.;
- Ghalwash, Mohamed;
- Li, Ying;
- Ng, Kenney;
- Dunne, Jessica L.;
- Lundgren, Markus;
- Hagopian, William;
- Lou, Olivia;
- Winkler, Christiane;
- Toppari, Jorma;
- Veijola, Riitta;
- Anand, Vibha;
- Ziegler, Anette G.;
- Bonifacio, Ezio;
- Achenbach, Peter;
- Rewers, Marian;
- Norris, Jill;
- Steck, Andrea;
- Waugh, Kathleen;
- Yu, Liping
Publication type:
Article
Islet Autoantibody Type-Specific Titer Thresholds Improve Stratification of Risk of Progression to Type 1 Diabetes in Children.
Published in:
2022
By:
- Ng, Kenney;
- Stavropoulos, Harry;
- Anand, Vibha;
- Veijola, Riitta;
- Toppari, Jorma;
- Maziarz, Marlena;
- Lundgren, Markus;
- Waugh, Kathy;
- Frohnert, Brigitte I.;
- Martin, Frank;
- Hagopian, William;
- Achenbach, Peter;
- T1DI Study Group
Publication type:
journal article
Islet Autoimmunity and HLA Markers of Presymptomatic and Clinical Type 1 Diabetes: Joint Analyses of Prospective Cohort Studies in Finland, Germany, Sweden, and the U.S.
Published in:
2021
By:
- Anand, Vibha;
- Ying Li;
- Bin Liu;
- Ghalwash, Mohamed;
- Koski, Eileen;
- Ng, Kenney;
- Dunne, Jessica L.;
- Jonsson, Josefine;
- Winkler, Christiane;
- Knip, Mikael;
- Toppari, Jorma;
- Honen, Jorma;
- Killian, Michael B.;
- Frohnert, Brigitte I.;
- Lundgren, Markus;
- Ziegler, Anette-Gabriele;
- Hagopian, William;
- Veijola, Riitta;
- Rewers, Marian;
- Li, Ying
Publication type:
journal article
Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-17374-3
By:
- Fahed, Akl C.;
- Wang, Minxian;
- Homburger, Julian R.;
- Patel, Aniruddh P.;
- Bick, Alexander G.;
- Neben, Cynthia L.;
- Lai, Carmen;
- Brockman, Deanna;
- Philippakis, Anthony;
- Ellinor, Patrick T.;
- Cassa, Christopher A.;
- Lebo, Matthew;
- Ng, Kenney;
- Lander, Eric S.;
- Zhou, Alicia Y.;
- Kathiresan, Sekar;
- Khera, Amit V.
Publication type:
Article
The MELD-Plus: A generalizable prediction risk score in cirrhosis.
Published in:
PLoS ONE, 2017, v. 12, n. 10, p. 1, doi. 10.1371/journal.pone.0186301
By:
- Kartoun, Uri;
- Corey, Kathleen E.;
- Simon, Tracey G.;
- Zheng, Hui;
- Aggarwal, Rahul;
- Ng, Kenney;
- Shaw, Stanley Y.
Publication type:
Article
Islet Autoantibody Levels Differentiate Progression Trajectories in Individuals With Presymptomatic Type 1 Diabetes.
Published in:
Diabetes, 2022, v. 71, n. 12, p. 2632, doi. 10.2337/db22-0360
By:
- Kwon, Bum Chul;
- Achenbach, Peter;
- Anand, Vibha;
- Frohnert, Brigitte I.;
- Hagopian, William;
- Hu, Jianying;
- Koski, Eileen;
- Lernmark, Åke;
- Lou, Olivia;
- Martin, Frank;
- Ng, Kenney;
- Toppari, Jorma;
- Veijola, Riitta
Publication type:
Article
65-OR: Autoantibody Levels at Seroconversion Improve Prediction to Type 1 Diabetes Beyond Autoantibody Type and Number.
Published in:
Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-65-OR
By:
- NG, KENNEY;
- ANAND, VIBHA;
- VEIJOLA, RIITTA;
- MAZIARZ, MARLENA;
- WAUGH, KATHLEEN;
- HAGOPIAN, WILLIAM;
- ACHENBACH, PETER
Publication type:
Article
1690-P: Predicting Onset of Type 1 Diabetes Using a Novel Interaction Model.
Published in:
Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-1690-P
By:
- LIU, BIN;
- ANAND, VIBHA;
- GHALWASH, MOHAMED;
- NG, KENNEY;
- DUNNE, JESSICA L.;
- VEIJOLA, RIITTA;
- REWERS, MARIAN;
- LUNDGREN, MARKUS
Publication type:
Article
163-OR: Sensitivity Analysis of Alternate Definitions of Multiple Islet Autoantibody Positivity.
Published in:
Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-163-OR
By:
- LIU, BIN;
- GHALWASH, MOHAMED;
- ANAND, VIBHA;
- KOSKI, EILEEN;
- NG, KENNEY;
- DUNNE, JESSICA L.;
- LUNDGREN, MARKUS;
- LARSSON, HELENA ELDING;
- HAGOPIAN, WILLIAM;
- VEIJOLA, RIITTA;
- FROHNERT, BRIGITTE I.
Publication type:
Article
1345-P: Presymptomatic and Clinical T1D in The U.S., Sweden, and Finland: Joint Analysis of Four Birth Cohort Studies.
Published in:
Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-1345-P
By:
- ANAND, VIBHA;
- LIU, BIN;
- GHALWASH, MOHAMED;
- KOSKI, EILEEN;
- NG, KENNEY;
- DUNNE, JESSICA L.;
- HAGOPIAN, WILLIAM;
- LUNDGREN, MARKUS;
- LERNMARK, ÅKE;
- ILONEN, JORMA;
- VEIJOLA, RIITTA;
- REWERS, MARIAN
Publication type:
Article
211-OR: Analysis of Longitudinal Autoantibody Profiles and the Progression Rates to Type 1 Diabetes.
Published in:
Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-211-OR
By:
- GHALWASH, MOHAMED;
- ANAND, VIBHA;
- LIU, BIN;
- KOSKI, EILEEN;
- NG, KENNEY;
- DUNNE, JESSICA L.;
- LUNDGREN, MARKUS;
- REWERS, MARIAN;
- VEIJOLA, RIITTA
Publication type:
Article

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