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- Title
Synthesis of polysubstituted β-amino cyclohexane carboxylic acids via Diels-Alder reaction using Ni(II)-complex stabilized β-alanine derived dienes.
- Authors
Ding, Xiao; Wang, Hengshuai; Wang, Jiang; Wang, Sinan; Lin, Daizong; Lv, Li; Zhou, Yu; Luo, Xiaomin; Jiang, Hualiang; Aceña, José; Soloshonok, Vadim; Liu, Hong
- Abstract
This paper describes the design and synthesis of a new class of β-alanine derived dienes stabilized by Ni(II)-complex. Preliminary study of their Diels-Alder cycloaddition reactions with several types of dienophiles demonstrates their significant synthetic potential for the preparation of various polyfunctional β-aminocyclohexane carboxylic acids.
- Subjects
SUBSTITUENTS (Chemistry); CYCLOHEXANE; CARBOXYLIC acids; DIELS-Alder reaction; ALANINE; CHEMICAL derivatives; CYCLOHEXYLAMINE
- Publication
Amino Acids, 2013, Vol 44, Issue 2, p791
- ISSN
0939-4451
- Publication type
Article
- DOI
10.1007/s00726-012-1404-x