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- Title
Improved 8-Year Survival for Patients With Stage IIIC Ovarian Cancer Operated on at Teaching Hospitals: Population-Based Study in Norway 2002.
- Authors
Paulsen, Torbjørn; Szczesny, Witold; Kærn, Janne; Vistad, Ingvild; Tropé, Claes
- Abstract
This study aimed to determine how hospital level influenced long-term survival for patients with advanced ovarian cancer. The study population was registered in a prospective population-based registry. All 198 women in Norway with ovarian cancer International Federation of Gynecology and Obstetrics (FIGO) stage IIIC with primary diagnosis during 2002 were included. Patients operated on at teaching hospitals (THs) achieved better 8-year survival than did patients operated on at nonteaching hospitals (NTHs). Background: The aim of this study was to find out the long-term survival of patients with primary International Federation of Gynecology and Obstetrics (FIGO) stage IIIC epithelial ovarian cancer (EOC IIIC) in a population-based patient cohort treated in Norway in 2002. Patients and Methods: All 198 women with a diagnosis of EOC IIIC who underwent surgery were included. The data were derived from notifications to the Norwegian Cancer Registry and medical, surgical, and histopathologic records. The hospitals were grouped into teaching hospitals (THs) and nonteaching hospitals (NTHs). The follow-up period was from 0 to 106 months. Results: The long-term survival at 8 years was 15% for women operated on at THs and 10% for women operated on at NTHs (P < .05). The median survival was 35.6 months at THs and 23.4 months at NTHs (P<.05). After simultaneous adjustment for 4 prognostic factors (age, histologic type, grade of differentiation, and residual disease), the risk of death within 8 years at NTHs was unchanged, with a hazard ratio of 1.38 (95% confidence interval [CI], 1.00-1.89), compared with THs. Conclusion: Patients operated on for EOC IIIC at THs achieved better long-term survival than did patients operated on at NTHs. Centralization of EOC IIIC surgery should be introduced in all countries to improve outcomes for this patient group.
- Publication
Clinical Ovarian & Other Gynecologic Cancer, 2012, Vol 5, Issue 2, p60
- ISSN
2212-9553
- Publication type
Article
- DOI
10.1016/j.cogc.2012.12.002