We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Management of bleeding disorders in adults.
- Authors
PEYVANDI, F.; KLAMROTH, R.; CARCAO, M.; FEDERICI, A. B.; DI MINNO, G.; JIMÉNEZ-YUSTE, V.; RODRIGUEZ MERCHÁN, E. C.
- Abstract
. Development of FVIII inhibitors is currently the most severe and challenging complication of haemophilia A treatment and represents a very large economic burden for a chronic disease. As a result, clinical research is making major efforts to optimize the therapeutic approaches for this condition. In this section we will review some important aspects of the management of haemophilia in adults, including an overview of bleeding in women with von Willebrand disease, an analysis of FVIII consumption in patients with severe haemophilia A, an update of the ongoing RES.I.ST study, long-term prophylaxis and experience from the Pro.Will study, current evidence relating to economic aspects of the treatment of haemophilic patients with inhibitors (based on the PROFIT study), and an overview of musculoskeletal complications in adults with severe bleeding disorders.
- Subjects
BLOOD coagulation disorders; HEMOPHILIA; HEMORRHAGE; VON Willebrand disease; CHRONIC diseases
- Publication
Haemophilia, 2012, Vol 18, p24
- ISSN
1351-8216
- Publication type
Article
- DOI
10.1111/j.1365-2516.2012.02797.x