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- Title
Prenatal diagnosis of criss-cross heart: sonographical and pathological features of five cases.
- Authors
Li, S; Luo, G; Norwitz, E R; Wang, C; Ouyang, S; Yao, Y; Wen, H; Chen, C; Fu, Q; Xia, X; Bi, J; Zhu, J
- Abstract
Objective:To describe the sonographical and pathological features of fetal criss-cross heart (CCH).Study Design:All cases of fetal CCH diagnosed by fetal echocardiogram from May 2003-May 2011 were identified at a single referral center using an established perinatal database. Demographic and genetic information, sonographical images and autopsy reports were reviewed. Sonographical and pathological features are described.Result:Five cases of fetal CCH were identified, all of which were confirmed by autopsy. Characteristic sonographical findings include: (1) the inability to obtain four-chamber view at standard transverse plane through the fetal chest; (2) appreciation of the misaligned spatial atrial-ventricle connection with the interventricular septum in a 'spiraling' orientation; (3) orientation of the two ventricular inlets in a superior-inferior and crossing position; and (4) a four-chamber-like view seen in the sagittal plane of the fetal chest. Doppler ultrasound demonstrates the 'criss-cross' arrangement of the inflow tracts into the two ventricles simultaneously in the transverse plane of the fetal chest.Conclusion:CCH is a rare developmental disorder that can be accurately diagnosed prenatally. Early diagnosis will allow for more targeted counseling and early intervention.
- Subjects
CHINA; ACADEMIC medical centers; CONGENITAL heart disease; CASE studies; PRENATAL diagnosis; RESEARCH funding
- Publication
Journal of Perinatology, 2013, Vol 33, Issue 2, p98
- ISSN
0743-8346
- Publication type
Article
- DOI
10.1038/jp.2012.56