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- Title
Lack of replication of association between GIGYF2 variants and Parkinson disease.
- Authors
Bras, Jose; Simón-Sánchez, Javier; Federoff, Monica; Morgadinho, Ana; Januario, Cristina; Ribeiro, Maria; Cunha, Luis; Oliveira, Catarina; Singleton, Andrew B.
- Abstract
Mutations in GIGYF2 have recently been described as causative of Parkinson's disease in Europeans. In an attempt to replicate these results in independent populations, we sequenced the entire coding region of GIGYF2 in a large series of Portuguese and North American samples. We report the finding of two of the previously published mutations in neurologically normal Control individuals. This suggests that mutations in GIGYF2 are not strongly related to the development of the disease in either of these populations.
- Publication
Human Molecular Genetics, 2009, Vol 18, Issue 2, p341
- ISSN
0964-6906
- Publication type
Article