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- Title
Common carotid and brachial artery hemodynamic alterations in periodontal disease.
- Authors
Carallo, Claudio; Franceschi, Maria Serena; Tripolino, Cesare; Figliuzzi, Michele; Irace, Concetta; Fortunato, Leonzio; Gnasso, Agostino
- Abstract
Aim In patients affected by periodontal disease, hypertension and systemic inflammation might cause an arterial hemodynamic derangement; this, in turn, can act as a mediator of the atherogenic process often seen in these patients. This study aimed at a comprehensive hemodynamic evaluation in periodontal patients. Methods Fourty-eight subjects participating to a cardiovascular prevention programme were enrolled. Periodontitis, classical risk factors for atherosclerosis, and shear and tensile forces in both carotid and brachial arteries were evaluated. Calculated periodontal indexes were plaque, gingival and pocket deep ( PD) indexes. Simple and multiple regression analyses were performed. Afterwards, 30 of them with normal PD index were compared with 30 carefully - matched patients with periodontitis. Results Brachial and carotid parietal tension were significantly associated with periodontal indexes, especially PD-Sum, in both simple ( r = 0.42, p < 0.001 for carotid artery and r = 0.36, p < 0.02 for brachial artery) and multiple regression analyses. Shear stress gave similar results. In case-control analysis, shear stress was lower by 15% and 30%, respectively, in carotid and brachial artery in patients with high PD; common carotid parietal tension was higher. Arterial stiffness resulted not associated with periodontitis. Conclusions Periodontal disease is associated to a complex atherosclerotic prone hemodynamic derangement, particularly in large elastic arteries.
- Subjects
ITALY; VASCULAR diseases; CAROTID artery abnormalities; DOPPLER ultrasonography; BLOOD testing; CHI-squared test; ELASTICITY; MULTIVARIATE analysis; PERIODONTAL disease; PHYSICAL diagnosis; REGRESSION analysis; SHEAR (Mechanics); PHYSIOLOGICAL stress; T-test (Statistics); EQUIPMENT &; supplies; BRACHIAL artery; CASE-control method; DESCRIPTIVE statistics; DISEASE complications; DISEASE risk factors
- Publication
Journal of Clinical Periodontology, 2013, Vol 40, Issue 5, p431
- ISSN
0303-6979
- Publication type
Article
- DOI
10.1111/jcpe.12099