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- Title
Predictores radiómicos F18-FDG PET/CT en la respuesta patológica completa a la quimioterapia neoadyuvante en pacientes con cáncer de mama.
- Authors
Lanzarin-Minero, Abel M.; Reyes-Gonzalez, J. Pablo; Fajardo-Fregoso, B. Fabiola
- Abstract
Objective: The objective of the study was to evaluate the diagnostic performance of the radiomic predictors F18-FDG PET/CT in the complete pathological response to neoadju vant chemotherapy in patients with breast cancer. Material and methods: A total of 127 records were used to make up a mock data set and 19 were included in the final analysis. Age, response to treatment and radiomic characteristics were analyzed. Results: The distribution of response to treatment was partial in 13 patients (68.42%), total response in three patients (15.79%), stability in two patients (19.53%) and progression in one patient (5.26 %). A packed ensemble of a LightGBM model was constructed in 3 folds given 85 original features from the input dataset. Conclusion: Diagnostic performance of radiomics features superior to the gold standard was shown. Although the usefulness of this approach in correct and early prediction of treatment has yet to be demonstrated, this study suggests that texture radiomics obtained by PET/CT may be useful in predicting response to treatment.
- Publication
Anales de Radiologia, Mexico, 2022, Vol 21, Issue 4, p225
- ISSN
1665-2118
- Publication type
Article
- DOI
10.24875/ARM.22000027