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- Title
Racial differences in patients with adenocarcinoma of the endometrium.
- Authors
Cronjé, H.S.; Fourie, S.; Doman, M.J.; Helms, J.B.; Nel, J.T.; Goedhals, L.; Cronjé, H S
- Abstract
<bold>Objective: </bold>To determine the differences between white and black women with regard to the presentation and behavior of adenocarcinoma of the endometrium.<bold>Method: </bold>Records of 273 (68%) white patients and 117 (32%) black patients with endometrial adenocarcinoma were reviewed in Bloemfontein, South Africa. Survival data was calculated according to the direct method where losses in follow-up were regarded as tumor deaths.<bold>Results: </bold>Most patients (82%) were treated by pre-operative radium followed by total abdominal hysterectomy and bilateral salpingo-oophorectomy, with post-operative external irradiation where indicated. Pre-operatively, fewer black women had reached FIGO stage I, while a larger number had advanced to stages II-IV (P = 0.0024). In addition, the tumor differentiation was more often poor in the black group (P < 0.0001). Ten-year follow-up was achieved in 84% of the white patients and 51% of the black patients and the 10-year survival figures were 67% for white patients and 28% for blacks (P < 0.0001).<bold>Conclusion: </bold>Endometrial adenocarcinoma is a more aggressive disease in black women than it is in whites.
- Publication
International Journal of Gynecology & Obstetrics, 1992, Vol 39, Issue 3, p213
- ISSN
0020-7292
- Publication type
journal article
- DOI
10.1016/0020-7292(92)90659-7